M L Uhler1, J W Marks, H L Judd. 1. Department of Obstetrics and Gynecology, Loyola University Medical Center, Maywood, Illinois 60153, USA.
Abstract
OBJECTIVE: To examine the role of estrogen replacement therapy on the development of gallbladder disease in postmenopausal women. DESIGN: Systematic review of the English literature was conducted. All studies that addressed the association between hormone replacement therapy and gallbladder disease published from 1970 to the present were reviewed. RESULTS: Seven observational studies, two clinical trials, two case series, and one nonrandomized and three randomized investigations were reviewed. The results of each study were reported and analyzed. CONCLUSIONS: Estrogen replacement therapy in postmenopausal women increased the chances for gallstone formation.
OBJECTIVE: To examine the role of estrogen replacement therapy on the development of gallbladder disease in postmenopausal women. DESIGN: Systematic review of the English literature was conducted. All studies that addressed the association between hormone replacement therapy and gallbladder disease published from 1970 to the present were reviewed. RESULTS: Seven observational studies, two clinical trials, two case series, and one nonrandomized and three randomized investigations were reviewed. The results of each study were reported and analyzed. CONCLUSIONS: Estrogen replacement therapy in postmenopausal women increased the chances for gallstone formation.
Authors: G Andreotti; L Hou; Y-T Gao; L A Brinton; A Rashid; J Chen; M-C Shen; B-S Wang; T-Q Han; B-H Zhang; L C Sakoda; J F Fraumeni; A W Hsing Journal: Br J Cancer Date: 2010-03-09 Impact factor: 7.640
Authors: Sue K Park; Gabriella Andreotti; Lori C Sakoda; Yu-Tang Gao; Asif Rashid; Jinbo Chen; Bingshu E Chen; Philip S Rosenberg; Ming-Chang Shen; Bing-Sheng Wang; Tian-Quan Han; Bai-He Zhang; Meredith Yeager; Stephen Chanock; Ann W Hsing Journal: Carcinogenesis Date: 2009-01-23 Impact factor: 4.944