Literature DB >> 1081095

The electroretinogram in dogs with inherited cone degeneration.

G D Aguirre, L F Rubin.   

Abstract

The electroretinogram (ERG) of hemeralopic Alaskan malamute dogs contains only rod components. There is absence of the photopic b-wave which is normally elicited with red light stimuli during dark adaptation and, using flicker stimulation, only the first or rod branch of the flicker fusion response curve is present. At high stimulus intensity levels, the flicker response of hemeralopes is absent. A normal ERG is recorded from affected dogs using blue light stimuli and low intensity white light. In the adult hemeralope, the retina contains no cones.

Entities:  

Mesh:

Year:  1975        PMID: 1081095

Source DB:  PubMed          Journal:  Invest Ophthalmol        ISSN: 0020-9988


  14 in total

Review 1.  Genetic and phenotypic variations of inherited retinal diseases in dogs: the power of within- and across-breed studies.

Authors:  Keiko Miyadera; Gregory M Acland; Gustavo D Aguirre
Journal:  Mamm Genome       Date:  2011-11-08       Impact factor: 2.957

Review 2.  Gene replacement therapy for retinal CNG channelopathies.

Authors:  Christian Schön; Martin Biel; Stylianos Michalakis
Journal:  Mol Genet Genomics       Date:  2013-07-17       Impact factor: 3.291

Review 3.  The function of dog models in developing gene therapy strategies for human health.

Authors:  Keri L Nowend; Alison N Starr-Moss; Keith E Murphy
Journal:  Mamm Genome       Date:  2011-07-06       Impact factor: 2.957

Review 4.  What do dogs (Canis familiaris) see? A review of vision in dogs and implications for cognition research.

Authors:  Sarah-Elizabeth Byosiere; Philippe A Chouinard; Tiffani J Howell; Pauleen C Bennett
Journal:  Psychon Bull Rev       Date:  2018-10

5.  Rod and cone components in the compound ERG of the beagle dog.

Authors:  U Schaeppi; F Liverani
Journal:  Agents Actions       Date:  1979-08

6.  Gene therapy rescues cone function in congenital achromatopsia.

Authors:  András M Komáromy; John J Alexander; Jessica S Rowlan; Monique M Garcia; Vince A Chiodo; Asli Kaya; Jacqueline C Tanaka; Gregory M Acland; William W Hauswirth; Gustavo D Aguirre
Journal:  Hum Mol Genet       Date:  2010-04-08       Impact factor: 6.150

7.  Use of extended protocols with nonstandard stimuli to characterize rod and cone contributions to the canine electroretinogram.

Authors:  Nate Pasmanter; Laurence M Occelli; András M Komáromy; Simon M Petersen-Jones
Journal:  Doc Ophthalmol       Date:  2022-03-05       Impact factor: 2.379

8.  Targeting gene expression to cones with human cone opsin promoters in recombinant AAV.

Authors:  A M Komáromy; J J Alexander; A E Cooper; V A Chiodo; L G Glushakova; G M Acland; W W Hauswirth; G D Aguirre
Journal:  Gene Ther       Date:  2008-03-13       Impact factor: 5.250

9.  Evaluation of a behavioral method for objective vision testing and identification of achromatopsia in dogs.

Authors:  Monique M Garcia; Gui-shuang Ying; Christina A Cocores; Jacqueline C Tanaka; András M Komáromy
Journal:  Am J Vet Res       Date:  2010-01       Impact factor: 1.156

10.  Genomic deletion of CNGB3 is identical by descent in multiple canine breeds and causes achromatopsia.

Authors:  Connie Y Yeh; Orly Goldstein; Anna V Kukekova; Debbie Holley; Amy M Knollinger; Heather J Huson; Susan E Pearce-Kelling; Gregory M Acland; András M Komáromy
Journal:  BMC Genet       Date:  2013-04-20       Impact factor: 2.797

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