Literature DB >> 10810742

Enantioselective synthesis of 2-substituted cyclobutanones

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Abstract

[formula: see text] An enantioselective synthesis of 2-substituted cyclobutanones has been achieved by sequential application of the titanium-mediated cyclopropanation of alpha-hydroxy esters and the pinacol-type rearrangement of the resulting alpha-hydroxycyclopropylcarbinols.

Entities:  

Year:  2000        PMID： 10810742     DOI： 10.1021/ol005820v

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  Applications of 1-alkenyl-1,1-heterobimetallics in the stereoselective synthesis of cyclopropylboronate esters, trisubstituted cyclopropanols and 2,3-disubstituted cyclobutanones.

Authors:  Mahmud M Hussain; Hongmei Li; Nusrah Hussain; Mercedes Ureña; Patrick J Carroll; Patrick J Walsh
Journal:  J Am Chem Soc       Date:  2009-05-13       Impact factor: 15.419

2.  Stereocontrolled synthesis and functionalization of cyclobutanes and cyclobutanones.

Authors:  Francesco Secci; Angelo Frongia; Pier Paolo Piras
Journal:  Molecules       Date:  2013-12-13       Impact factor: 4.411
  2 in total

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