| Literature DB >> 10810730 |
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Abstract
[formula: see text] A method for the highly stereoselective synthesis of 1,3-amino alcohols based on the indium trichloride-catalyzed Mukaiyama aldol reaction of keto ester (R,S)-1 under solvent-free conditions has been developed. The high selectivity observed can be explained on the basis of the shielding of one face by a remote substituent.Entities:
Year: 2000 PMID： 10810730 DOI： 10.1021/ol000042s
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005