| Literature DB >> 1081049 |
A F Pearlmutter, E Rapino, M Saffran.
Abstract
Gel filtration of an extract of rat median eminence tissue in 0.1 N HCl on Sephadex G-25 separated two peaks, both with feeble ACTH-releasing activity. Full activity of the extract was regained when both peaks were recombined. This observation suggests that the ACTH-releasing hormone of the hypothalamus requires a co-factor for activity.Entities:
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Year: 1975 PMID: 1081049 DOI: 10.1210/endo-97-5-1336
Source DB: PubMed Journal: Endocrinology ISSN: 0013-7227 Impact factor: 4.736