Literature DB >> 10809460

Withholding versus withdrawing life-sustaining treatment: patient factors and documentation associated with dialysis decisions.

N S Wenger1, J Lynn, R K Oye, H Liu, J M Teno, R S Phillips, N A Desbiens, A Sehgal, P Kussin, H Taub, F Harrell, W Knaus.   

Abstract

OBJECTIVE: We evaluated prospectively the use of acute hemodialysis among hospitalized patients to identify demographic and clinical predictors of and chart documentation concerning dialysis withheld and withdrawn.
DESIGN: Prospective cohort study.
SETTING: Five teaching hospitals. PATIENTS: Five hundred sixty-five seriously ill hospitalized patients who had not previously undergone dialysis who developed renal failure. MAIN OUTCOME MEASURES: Patient demographics, clinical characteristics, preferences, and prognostic estimates associated with having dialysis withheld rather than initiated and withdrawn rather than continued. Differences in chart documentation concerning decision-making for dialysis withheld, withdrawn, and continued.
RESULTS: Older patient age, cancer diagnosis, and male gender were associated with dialysis withheld rather than withdrawn. Age and gender differences persisted after adjustment for patients' aggressiveness of care preference. Worse 2-month prognosis was associated with both withholding and withdrawing dialysis. Chart documentation of decision-making was lacking more often for patients with dialysis withheld than for dialysis withdrawn.
CONCLUSIONS: Measuring the equity of life-sustaining treatment use will require evaluation of care withheld, not just care withdrawn. Older patients and men, after accounting for prognosis and function, are more likely to have dialysis withheld than withdrawn after a trial. Further exploration is needed into this disparity and the inadequate chart documentation for patients with dialysis withheld.

Entities:  

Keywords:  Death and Euthanasia; Empirical Approach

Mesh:

Year:  2000        PMID: 10809460     DOI: 10.1111/j.1532-5415.2000.tb03145.x

Source DB:  PubMed          Journal:  J Am Geriatr Soc        ISSN: 0002-8614            Impact factor:   5.562


  6 in total

1.  Decisions concerning potentially life-sustaining treatments in paediatric nephrology: a multicentre study in French-speaking countries.

Authors:  Isabelle Fauriel; Grégoire Moutel; Marie-Laure Moutard; Luc Montuclard; Nathalie Duchange; Ingrid Callies; Irène François; Pierre Cochat; Christian Hervé
Journal:  Nephrol Dial Transplant       Date:  2004-02-19       Impact factor: 5.992

2.  Effects of continuous and intermittent renal replacement therapies among adult patients with acute kidney injury.

Authors:  Tonio Schoenfelder; Xiaoyu Chen; Hans-Holger Bleß
Journal:  GMS Health Technol Assess       Date:  2017-03-01

3.  Dialysis-related practice patterns among hemodialysis patients with cancer.

Authors:  Hiroki Nishiwaki; Shingo Fukuma; Takeshi Hasegawa; Miho Kimachi; Tadao Akizawa; Shunichi Fukuhara
Journal:  Health Sci Rep       Date:  2018-05-16

4.  Provision of renal care for patients with end stage kidney disease in persistent vegetative state, in United Arab Emirates: a national survey of renal physicians.

Authors:  Fayez Ebrahim Alshamsi; Ahmed Chaaban; Mona Alrukhaimi; Bassam Bernieh; Omran Bakoush
Journal:  Libyan J Med       Date:  2018-12       Impact factor: 1.657

5.  Attitudes and behaviors of Japanese physicians concerning withholding and withdrawal of life-sustaining treatment for end-of-life patients: results from an Internet survey.

Authors:  Seiji Bito; Atsushi Asai
Journal:  BMC Med Ethics       Date:  2007-06-19       Impact factor: 2.652

Review 6.  Cancer and the kidney: dangereoux liasons or price paid for the progress in medicine?

Authors:  Jolanta Małyszko; Leszek Kozlowski; Klaudia Kozłowska; Maciej Małyszko; Jacek Małyszko
Journal:  Oncotarget       Date:  2017-05-23
  6 in total

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