Literature DB >> 10807544

p24/ING1-ALT1 and p47/ING1-ALT2, distinct alternative transcripts of p33/ING1.

A Saito1, T Furukawa, S Fukushige, S Koyama, M Hoshi, Y Hayashi, A Horii.   

Abstract

p33/ING1s (the growth inhibitor ING1 and candidate tumor suppressor ING1) are key players in the suppressive pathways for human tumorigenesis. We analyzed their complete transcripts, primary structures, and expression. The results led us to discover two novel and related alternatively spliced transcripts encoding p24/ING1-ALT1 and p47/ING1-ALT2. They share C-terminal residues with the candidate tumor suppressors p33/ING1. The candidate tumor suppressors p33/ING1 and p24/ING1-ALT1 were coexpressed in a variety of fetal and adult human tissues, but p47/ING1-ALT2 was minimally expressed.

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Year:  2000        PMID： 10807544     DOI： 10.1007/s100380050206

Source DB:  PubMed          Journal:  J Hum Genet        ISSN： 1434-5161            Impact factor:   3.172


  13 in total

1.  Exploration of novel motifs derived from mouse cDNA sequences.

Authors:  Hideya Kawaji; Christian Schönbach; Yo Matsuo; Jun Kawai; Yasushi Okazaki; Yoshihide Hayashizaki; Hideo Matsuda
Journal:  Genome Res       Date:  2002-03       Impact factor: 9.043

2.  UV induces nucleolar translocation of ING1 through two distinct nucleolar targeting sequences.

Authors:  M Scott; F M Boisvert; D Vieyra; R N Johnston; D P Bazett-Jones; K Riabowol
Journal:  Nucleic Acids Res       Date:  2001-05-15       Impact factor: 16.971

Review 3.  The ING family tumor suppressors: from structure to function.

Authors:  Almass-Houd Aguissa-Touré; Ronald P C Wong; Gang Li
Journal:  Cell Mol Life Sci       Date:  2010-08-29       Impact factor: 9.261

4.  DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53.

Authors:  M Nagashima; M Shiseki; K Miura; K Hagiwara; S P Linke; R Pedeux; X W Wang; J Yokota; K Riabowol; C C Harris
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-31       Impact factor: 11.205

5.  Growth inhibition by the tumor suppressor p33ING1 in immortalized and primary cells: involvement of two silencing domains and effect of Ras.

Authors:  Frauke Goeman; Dorit Thormeyer; Maria Abad; Manuel Serrano; Oliver Schmidt; Ignacio Palmero; Aria Baniahmad
Journal:  Mol Cell Biol       Date:  2005-01       Impact factor: 4.272

6.  The expression of p33(ING1), p53, and autophagy-related gene Beclin1 in patients with non-small cell lung cancer.

Authors:  Jun Liu; Yongping Lin; Haihong Yang; Qiuhua Deng; Guoqin Chen; Jianxing He
Journal:  Tumour Biol       Date:  2011-07-22

Review 7.  The role of the tumour suppressor p33 ING1b in human neoplasia.

Authors:  G S Nouman; J J Anderson; J Lunec; B Angus
Journal:  J Clin Pathol       Date:  2003-07       Impact factor: 3.411

8.  Cytoplasmic expression of p33(ING1b) is correlated with tumorigenesis and progression of human esophageal squamous cell carcinoma.

Authors:  Zhen-Long Zhu; Bao-Yong Yan; Yu Zhang; Yan-Hong Yang; Zheng-Min Wang; Hong-Zhen Zhang; Ming-Wei Wang; Xiang-Hong Zhang; Xiao-Feng Sun
Journal:  Oncol Lett       Date:  2012-10-22       Impact factor: 2.967

9.  Loss of nuclear expression of the p33(ING1b) inhibitor of growth protein in childhood acute lymphoblastic leukaemia.

Authors:  G S Nouman; J J Anderson; K M Wood; J Lunec; A G Hall; M M Reid; B Angus
Journal:  J Clin Pathol       Date:  2002-08       Impact factor: 3.411

Review 10.  Reviewing the current classification of inhibitor of growth family proteins.

Authors:  Motoko Unoki; Kensuke Kumamoto; Seiichi Takenoshita; Curtis C Harris
Journal:  Cancer Sci       Date:  2009-04-28       Impact factor: 6.716
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