| Literature DB >> 1080708 |
T G Riddle, L J Mandel, M M Goldner.
Abstract
The effects of diphenylhydantoin (DPH) and calcium were simultaneously studied on solute transport in frog skin. In the presence of external Ca, DPH elicited a significant increase in active Na transport; in its absence, DPH had no significant effect on active transport. DPH increased passive permeability, but this action was independent of Ca. It appears that the increase in active transport elicited by DPH is due to a specific interaction with Ca at the transport site.Entities:
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Year: 1975 PMID： 1080708 DOI： 10.1016/0014-2999(75)90155-7
Source DB: PubMed Journal: Eur J Pharmacol ISSN： 0014-2999 Impact factor: 4.432