Literature DB >> 10806998

A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides.

A A Levin1.   

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Year:  1999        PMID: 10806998     DOI: 10.1016/s0167-4781(99)00140-2

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


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  101 in total

1.  Inhibition of telomerase by 2'-O-(2-methoxyethyl) RNA oligomers: effect of length, phosphorothioate substitution and time inside cells.

Authors:  A N Elayadi; A Demieville; E V Wancewicz; B P Monia; D R Corey
Journal:  Nucleic Acids Res       Date:  2001-04-15       Impact factor: 16.971

Review 2.  Gene therapy for HIV.

Authors:  A M Lever
Journal:  Sex Transm Infect       Date:  2001-04       Impact factor: 3.519

3.  RNA cleaving '10-23' DNAzymes with enhanced stability and activity.

Authors:  Steffen Schubert; Deniz C Gül; Hans-Peter Grunert; Heinz Zeichhardt; Volker A Erdmann; Jens Kurreck
Journal:  Nucleic Acids Res       Date:  2003-10-15       Impact factor: 16.971

4.  NMR structure of an alpha-L-LNA:RNA hybrid: structural implications for RNase H recognition.

Authors:  Jakob T Nielsen; Paul C Stein; Michael Petersen
Journal:  Nucleic Acids Res       Date:  2003-10-15       Impact factor: 16.971

5.  The pharmacodynamic characterization of an antisense oligonucleotide against monoamine oxidase-B (MAO-B) in rat brain striatal tissue.

Authors:  J E Sprague; T J Worst; K Haynes; C R Mosler; D E Nichols; M D Kane
Journal:  Cell Mol Neurobiol       Date:  2001-02       Impact factor: 5.046

Review 6.  Silencing disease genes in the laboratory and the clinic.

Authors:  Jonathan K Watts; David R Corey
Journal:  J Pathol       Date:  2011-11-09       Impact factor: 7.996

7.  DeltaNp73 antisense activates PUMA and induces apoptosis in neuroblastoma cells.

Authors:  A P Simões-Wüst; B Sigrist; L Belyanskaya; S Hopkins Donaldson; R A Stahel; U Zangemeister-Wittke
Journal:  J Neurooncol       Date:  2005-03       Impact factor: 4.130

8.  PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice.

Authors:  Bradley A Zinker; Cristina M Rondinone; James M Trevillyan; Rebecca J Gum; Jill E Clampit; Jeffrey F Waring; Nancy Xie; Denise Wilcox; Peer Jacobson; Leigh Frost; Paul E Kroeger; Regina M Reilly; Sandra Koterski; Terry J Opgenorth; Roger G Ulrich; Seth Crosby; Madeline Butler; Susan F Murray; Robert A McKay; Sanjay Bhanot; Brett P Monia; Michael R Jirousek
Journal:  Proc Natl Acad Sci U S A       Date:  2002-08-08       Impact factor: 11.205

Review 9.  Targeted delivery systems for oligonucleotide therapeutics.

Authors:  Bo Yu; Xiaobin Zhao; L James Lee; Robert J Lee
Journal:  AAPS J       Date:  2009-03-19       Impact factor: 4.009

Review 10.  Crystallographic studies of chemically modified nucleic acids: a backward glance.

Authors:  Martin Egli; Pradeep S Pallan
Journal:  Chem Biodivers       Date:  2010-01       Impact factor: 2.408

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