Literature DB >> 10804122

[Nasal leishmaniasis in an HIV-positive patient].

J M Grasa1, J Lorente, F Crego, S Naches, F X Subirana, J R Calderón, C Pollán, L F Encarnación, P Quesada.   

Abstract

Leishmania is currently one of the most clinically important protozoa in otorhinolaryngology. Mediterranean countries, including Spain, have endemic HIV and L. infantum. Dogs are the most important Leishmania reservoir. Leishmaniasis is transmitted basically by the bite of infected female Phlebotomus sandflies. Its clinical development depends mainly on the host's cellular immunity (TCD4+ lymphocyte count). About 400 cases of HIV-visceral leishmaniasis have been reported in Spain. However, exclusively cutaneous presentation of HIV-leishmaniasis coinfection has been observed in only 2-3% of cases. We report the case of a female HIV+ patient who developed cutaneous leishmaniasis of the nasal vestibule by L. infantum. The patient was treated satisfactorily with a combination of parenteral Pentostam (sodium stilbogluconate) and periodic intralesional injections of Pentostam. The patient was included in a secondary prophylaxis protocol for visceral leishmaniasis with a monthly dose of Glucantime (meglumine antimoniate) for life.

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Year:  2000        PMID: 10804122

Source DB:  PubMed          Journal:  Acta Otorrinolaringol Esp        ISSN: 0001-6519


  2 in total

1.  Human immunodeficiency virus infection: personal experience in changes in head and neck manifestations due to recent antiretroviral therapies.

Authors:  A Campanini; M Marani; A Mastroianni; C Cancellieri; C Vicini
Journal:  Acta Otorhinolaryngol Ital       Date:  2005-02       Impact factor: 2.124

2.  In Vitro and In Vivo Control of Secondary Bacterial Infection Caused by Leishmania major.

Authors:  Hany M Yehia; Ebtesam M Al-Olayan; Manal F El-Khadragy; Dina M Metwally
Journal:  Int J Environ Res Public Health       Date:  2017-07-13       Impact factor: 3.390

  2 in total

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