Literature DB >> 1080274

Late sodium current in the node of Ranvier.

J M Dubois, C Bergman.   

Abstract

Voltage clamp experiments carried out on nodes of Ranvier of myelinated fibres of Rana esculenta showed that a small fractoon of sodium channels fail to inactivate. Thus during long lasting depolarizing pulses there is a small Na-current superimposed on the leakage and potassium currents. This late Na-current appears more marked in sensory fibres than in motor ones.

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Year:  1975        PMID: 1080274     DOI: 10.1007/bf00584552

Source DB:  PubMed          Journal:  Pflugers Arch        ISSN: 0031-6768            Impact factor:   3.657


  5 in total

1.  A QUANTITATIVE DESCRIPTION OF POTASSIUM CURRENTS IN MYELINATED NERVE FIBRES OF XENOPUS LAEVIS.

Authors:  B FRANKENHAEUSER
Journal:  J Physiol       Date:  1963-11       Impact factor: 5.182

2.  Instantaneous potassium currents in myelinated nerve fibres of Xenopus laevis.

Authors:  B FRANKENHAEUSER
Journal:  J Physiol       Date:  1962-01       Impact factor: 5.182

3.  Specific and unspecific charges at the sodium channels of the nerve membrane.

Authors:  H Drouin; B Neumcke
Journal:  Pflugers Arch       Date:  1974       Impact factor: 3.657

4.  A new voltage clamp method for Ranvier nodes.

Authors:  W Nonner
Journal:  Pflugers Arch       Date:  1969       Impact factor: 3.657

5.  Potassium accumulation in the perinodal space of frog myelinated axons.

Authors:  J M Dubois; C Bergman
Journal:  Pflugers Arch       Date:  1975-07-21       Impact factor: 3.657

  5 in total
  26 in total

1.  Conductance fluctuations in Ranvier nodes.

Authors:  R J van den Berg; J de Goede; A A Verveen
Journal:  Pflugers Arch       Date:  1975-10-16       Impact factor: 3.657

2.  Pharmacology and Toxicology of Nav1.5-Class 1 anti-arrhythmic drugs.

Authors:  Dan M Roden
Journal:  Card Electrophysiol Clin       Date:  2014-12-01

3.  Blocking Scn10a channels in heart reduces late sodium current and is antiarrhythmic.

Authors:  Tao Yang; Thomas C Atack; Dina Myers Stroud; Wei Zhang; Lynn Hall; Dan M Roden
Journal:  Circ Res       Date:  2012-06-20       Impact factor: 17.367

4.  Biophysical characterisation of the persistent sodium current of the Nav1.6 neuronal sodium channel: a single-channel analysis.

Authors:  Aurélien Chatelier; Juan Zhao; Patrick Bois; Mohamed Chahine
Journal:  Pflugers Arch       Date:  2010-03-05       Impact factor: 3.657

5.  Latent addition in motor and sensory fibres of human peripheral nerve.

Authors:  H Bostock; J C Rothwell
Journal:  J Physiol       Date:  1997-01-01       Impact factor: 5.182

6.  Interaction between bradykinin and voltage-sensitive sodium channels in myelinated nerve fibers.

Authors:  M R Carratù; D Mitolo-Chieppa
Journal:  Experientia       Date:  1989-04-15

7.  The steady-state potassium conductance of the Ranvier node at various external K-concentrations.

Authors:  J M Dubois; C Bergman
Journal:  Pflugers Arch       Date:  1977-08-29       Impact factor: 3.657

8.  Rate of action of Anemonia sulcata toxin II on sodium channels in myelinated nerve fibres.

Authors:  J Schmidtmayer; M Stoye-Herzog; W Ulbricht
Journal:  Pflugers Arch       Date:  1982-10-01       Impact factor: 3.657

9.  The steady state TTX-sensitive ("window") sodium current in cardiac Purkinje fibres.

Authors:  D Attwell; I Cohen; D Eisner; M Ohba; C Ojeda
Journal:  Pflugers Arch       Date:  1979-03-16       Impact factor: 3.657

10.  Electrophysiological characterization of the tetrodotoxin-resistant Na+ channel, Na(v)1.9, in mouse dorsal root ganglion neurons.

Authors:  Hiroshi Maruyama; Mitsuko Yamamoto; Tomoya Matsutomi; Taixing Zheng; Yoshihiro Nakata; John N Wood; Nobukuni Ogata
Journal:  Pflugers Arch       Date:  2004-10       Impact factor: 3.657

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