Chloride transport in isolated skin of Rana esculenta.

Using a modified Ussing chamber, transepithelial Cl transport in isolated skin of Rana esculenta was determined throughout the year. Unidirectional 36-Cl fluxes were measured in the absence of electrochemical gradients across the skin. The correlations between unidirectional Cl influx and Cl efflux respectively and the Cl concentration in Na containing solutions were not linear in the 0 to 90 meq/1 range. The net Cl influx calculated from these two correlations was, in the same concentration range, also not linearly correlated and was significantly different from zero...