Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 In and out of the postsynaptic region: signalling proteins on the move.

Literature DB >> 10802539

In and out of the postsynaptic region: signalling proteins on the move.

Abstract

Reversible translocation of signalling proteins to and from their sites of action has emerged as an important theme in signal transduction. The recent findings of the stimulus-induced translocation of Ca2+-calmodulin-dependent protein kinase II (CaMKII) and the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor to and from the postsynaptic region are model cases for understanding how the dynamic localization of signalling proteins is used to regulate signal transduction.

Entities: Gene

Mesh：

Substances：

Year: 2000 PMID： 10802539 DOI： 10.1016/s0962-8924(00)01764-5

Source DB: PubMed Journal: Trends Cell Biol ISSN： 0962-8924 Impact factor: 20.808

Keyword Cloud
Cited

10 in total

1. Signaling in small subcellular volumes. I. Stochastic and diffusion effects on individual pathways.

Authors: Upinder S Bhalla
Journal: Biophys J Date: 2004-08 Impact factor: 4.033

2. cAMP-dependent protein kinase inhibits α7 nicotinic receptor activity in layer 1 cortical interneurons through activation of D1/D5 dopamine receptors.

Authors: Pragya Komal; Jasem Estakhr; Melad Kamran; Anthony Renda; Raad Nashmi
Journal: J Physiol Date: 2015-06-25 Impact factor: 5.182

3. Transient versus asymptotic dynamics of CaM kinase II: possible roles of phosphatase.

Authors: Y Kubota; J M Bower
Journal: J Comput Neurosci Date: 2001 Nov-Dec Impact factor: 1.621

4. Alterations of CaMKII after hypoxia-ischemia during brain development.

Authors: Kaixiong Tang; Chunli Liu; John Kuluz; Bingren Hu
Journal: J Neurochem Date: 2004-10 Impact factor: 5.372

5. Nonclassical mechanisms of progesterone action in the brain: I. Protein kinase C activation in the hypothalamus of female rats.

Authors: Bhuvana Balasubramanian; Wendy Portillo; Andrea Reyna; Jian Zhong Chen; Anthony N Moore; Pramod K Dash; Shaila K Mani
Journal: Endocrinology Date: 2008-07-10 Impact factor: 4.736

In and out of the postsynaptic region: signalling proteins on the move.

1. Signaling in small subcellular volumes. I. Stochastic and diffusion effects on individual pathways.

2. cAMP-dependent protein kinase inhibits α7 nicotinic receptor activity in layer 1 cortical interneurons through activation of D1/D5 dopamine receptors.

3. Transient versus asymptotic dynamics of CaM kinase II: possible roles of phosphatase.

4. Alterations of CaMKII after hypoxia-ischemia during brain development.

5. Nonclassical mechanisms of progesterone action in the brain: I. Protein kinase C activation in the hypothalamus of female rats.

6. Propagation of CaMKII translocation waves in heterogeneous spiny dendrites.

7. CaMKII translocation requires local NMDA receptor-mediated Ca2+ signaling.

8. Molecular switches at the synapse emerge from receptor and kinase traffic.

9. Role of DARPP-32 and ARPP-21 in the Emergence of Temporal Constraints on Striatal Calcium and Dopamine Integration.

10. Subcellular dynamics of type II PKA in neurons.