Literature DB >> 10801407

How to activate p53.

T Caspari1.   

Abstract

The tumour suppressor protein p53 is stabilised and activated in response to ionising radiation. This is known to depend on the kinase ATM; recent results suggest ATM acts via the downstream kinase Chk2/hCds1, which stabilises p53 at least in part by direct phosphorylation of residue serine 20.

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Year:  2000        PMID： 10801407     DOI： 10.1016/s0960-9822(00)00439-5

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  44 in total

1.  Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage.

Authors:  L Anderson; C Henderson; Y Adachi
Journal:  Mol Cell Biol       Date:  2001-03       Impact factor: 4.272

Review 2.  The ubiquitin-proteasome pathway and proteasome inhibitors.

Authors:  J Myung; K B Kim; C M Crews
Journal:  Med Res Rev       Date:  2001-07       Impact factor: 12.944

3.  The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1.

Authors:  R Tiedt; B A Bartholdy; G Matthias; J W Newell; P Matthias
Journal:  EMBO J       Date:  2001-08-01       Impact factor: 11.598

4.  Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains.

Authors:  Pamela Ghioni; Fabrizio Bolognese; Pascal H G Duijf; Hans Van Bokhoven; Roberto Mantovani; Luisa Guerrini
Journal:  Mol Cell Biol       Date:  2002-12       Impact factor: 4.272

5.  E2F1 induces phosphorylation of p53 that is coincident with p53 accumulation and apoptosis.

Authors:  Harry A Rogoff; Mary T Pickering; Michelle E Debatis; Stephen Jones; Timothy F Kowalik
Journal:  Mol Cell Biol       Date:  2002-08       Impact factor: 4.272

6.  DNA damage response by single-strand breaks in terminally differentiated muscle cells and the control of muscle integrity.

Authors:  P Fortini; C Ferretti; B Pascucci; L Narciso; D Pajalunga; E M R Puggioni; R Castino; C Isidoro; M Crescenzi; E Dogliotti
Journal:  Cell Death Differ       Date:  2012-06-15       Impact factor: 15.828

7.  Activation of p38 MAP kinase by DNA double-strand breaks in V(D)J recombination induces a G2/M cell cycle checkpoint.

Authors:  Gustavo Pedraza-Alva; Miroslav Koulnis; Colette Charland; Tina Thornton; James L Clements; Mark S Schlissel; Mercedes Rincón
Journal:  EMBO J       Date:  2006-02-02       Impact factor: 11.598

8.  Deregulation of DNA damage signal transduction by herpesvirus latency-associated M2.

Authors:  Xiaozhen Liang; Mary T Pickering; Nam-Hyuk Cho; Heesoon Chang; Michael R Volkert; Timothy F Kowalik; Jae U Jung
Journal:  J Virol       Date:  2006-06       Impact factor: 5.103

9.  Involvement of ATM/ATR-p38 MAPK cascade in MNNG induced G1-S arrest.

Authors:  Ke-Qing Zhu; Suo-Jiang Zhang
Journal:  World J Gastroenterol       Date:  2003-09       Impact factor: 5.742

10.  Mutations in CHEK2 associated with prostate cancer risk.

Authors:  Xiangyang Dong; Liang Wang; Ken Taniguchi; Xianshu Wang; Julie M Cunningham; Shannon K McDonnell; Chiping Qian; Angela F Marks; Susan L Slager; Brett J Peterson; David I Smith; John C Cheville; Michael L Blute; Steve J Jacobsen; Daniel J Schaid; Donald J Tindall; Stephen N Thibodeau; Wanguo Liu
Journal:  Am J Hum Genet       Date:  2003-01-17       Impact factor: 11.025
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