[A comparison of myocardial infarction clinical course and long-term prognosis in the years 1977-85 and 1992-96].

This study describes comparison of the management in 997 patients treated in 1977-85 with acute transmural myocardial infarction (MI), their in-hospital and long-term mortality, with 881 patients treated in 1992-96. The study included geographically the same population treated by the same medical staff but in another decade period and the same MI criteria in both cohorts. Main changes were associated with the management of MI. Both groups were adjusted to age (59.3 +/- 11 vs. 59.9 +/- 11.7), history prior to myocardial infarction, diabetes mellitus, habit of smoking and hospital complications except rarer presence of block A-V II degrees and III degrees in the period 1992-96. The increase in percentage of female patients was noticed in the analysis (from 21% to 28.5%). The crude in-hospital mortality was statistically lower in 1992-96 than in 1977-85 (19.8% vs. 13.4% p < 0.11) and the follow up mortality in the next 2-6 years decreased from 6.97% to 4.95%. Mortality in the first year after MI in both periods was high and raised to 9.6% and 8.9%, respectively (NS). Significant diminish of mortality in next years after myocardial infarction was observed in all age adjusted groups of patients treated in 1992-96.