Literature DB >> 1080046

Anesthesia of the ear by iontophoresis of lidocaine.

D F Echols, C H Norris, H G Tabb.   

Abstract

Anesthesia of the tympanic membrane and ear canal by the use of iontophoresis of local anesthetics is a painless and safe method of anesthesia for office myringotomy and polyethylene tube insertion, and possibly for surgical use as well. With the use of guinea pig models, the introduction of 4% lidocaine hydrochloride solution in the middle ear space with iontophoresis revealed no toxic effects on the eighth nerve, and epinephrine hydrocloride potentiates the effects of lidocaine and has no protective mechanism on the eighth nerve function.

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Year:  1975        PMID: 1080046     DOI: 10.1001/archotol.1975.00780360018004

Source DB:  PubMed          Journal:  Arch Otolaryngol        ISSN: 0003-9977


  5 in total

1.  Iontophoresis with an adrenergic alpha-blocker in acoustic overstimulation.

Authors:  M Hildesheimer; C Muchnik; M Rubinstein
Journal:  Eur Arch Otorhinolaryngol       Date:  1990       Impact factor: 2.503

2.  lontophoretic Devices for Drug Delivery.

Authors:  P Tyle
Journal:  Pharm Res       Date:  1986-12       Impact factor: 4.200

3.  Iontophoretic application of adenine arabinoside monophosphate to herpes simplex virus type 1-infected hairless mouse skin.

Authors:  N H Park; L P Gangarosa; B S Kwon; J M Hill
Journal:  Antimicrob Agents Chemother       Date:  1978-10       Impact factor: 5.191

4.  The effect of alternating current iontophoresis on rats with the chronic constriction injury to the infraorbital nerve.

Authors:  Yoko Yamazaki; Masahiro Umino; Haruhisa Fukayama; Masahiko Shimada
Journal:  Int J Dent       Date:  2012-05-23

5.  Pharmacokinetics of Single Dose Lidocaine and Epinephrine Following Iontophoresis of the Tympanic Membrane in a Double-Blinded Randomized Trial.

Authors:  Laura J England; Charles A Syms; Christopher York
Journal:  Otol Neurotol       Date:  2021-08-01       Impact factor: 2.311

  5 in total

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