| Literature DB >> 10799805 |
G V Carbonell1, H H Della Colleta, T Yano, A L Darini, C E Levy, B A Fonseca.
Abstract
Pigmented Serratia marcescens isolated in a Brazilian hospital were studied with respect to frequency of isolation, serotyping, antibiotic resistance and virulence factors. The serotype most frequent was O6:K14 (53%) and all isolates were resistant to ampicillin, cephalothin and tetracycline. The majority of the isolates (92%) were resistant to the action of human serum and all produced cytotoxins on Vero, CHO, HEp-2 and HeLa cells. These isolates were virulent for mice (LD(50)=10(7) bacteria ml(-1)) and showed virulence factors, but were isolated with low frequency (3. 4%) and caused infection in only 31% of cases. Analysis of serotyping, phage typing and chromosomal DNA revealed at least 13 unrelated strains among pigmented S. marcescens. In conclusion, this work describes a low frequency of isolation of pigmented S. marcescens from clinical specimens, indicating that non-pigmented strains are clinically more significant.Entities:
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Year: 2000 PMID： 10799805 DOI： 10.1111/j.1574-695X.2000.tb01469.x
Source DB: PubMed Journal: FEMS Immunol Med Microbiol ISSN： 0928-8244