Literature DB >> 10796065

Imipenem but not meropenem induces convulsions in DBA/2 mice, unrelated to cerebrospinal fluid concentrations.

A Dupuis1, C Pariat, P Courtois, W Couet, S Bouquet.   

Abstract

Imipenem and meropenem CSF diffusion was comparable in DBA/2 mice but only imipenem induced convulsions, not related to CSF concentration.

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Year:  2000        PMID： 10796065     DOI： 10.1111/j.1472-8206.2000.tb00406.x

Source DB:  PubMed          Journal:  Fundam Clin Pharmacol        ISSN： 0767-3981            Impact factor:   2.748


  4 in total

1.  Pharmacokinetic-pharmacodynamic modeling of the electroencephalogram effect of imipenem in healthy rats.

Authors:  A Dupuis; W Couet; J Paquereau; S Debarre; A Portron; C Jamois; S Bouquet
Journal:  Antimicrob Agents Chemother       Date:  2001-06       Impact factor: 5.191

2.  Pharmacokinetic-pharmacodynamic modeling of the electroencephalogram effect of norfloxacin in rats.

Authors:  Marylore Chenel; Agnès Barbot; Antoine Dupuis; Olivier Mimoz; Joël Paquereau; Serge Bouquet; William Couet
Journal:  Antimicrob Agents Chemother       Date:  2003-06       Impact factor: 5.191

3.  Population Pharmacokinetics of High-Dose Continuous-Infusion Meropenem and Considerations for Use in the Treatment of Infections Due to KPC-Producing Klebsiella pneumoniae.

Authors:  Piergiorgio Cojutti; Assunta Sartor; Elda Righi; Claudio Scarparo; Matteo Bassetti; Federico Pea
Journal:  Antimicrob Agents Chemother       Date:  2017-09-22       Impact factor: 5.191

4.  Even apparently insignificant chemical deviations among bioequivalent generic antibiotics can lead to therapeutic nonequivalence: the case of meropenem.

Authors:  M Agudelo; C A Rodriguez; C A Pelaez; O Vesga
Journal:  Antimicrob Agents Chemother       Date:  2013-11-25       Impact factor: 5.191
  4 in total

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