| Literature DB >> 1079426 |
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Abstract
In two models of genetically determined, spontaneous autoimmune thyroiditis, neonatal thymectomy increases the incidience and severity of disease. The simpliest explanation is that the thymus, or thymus-derived cells, normally exert a suppressive effect on the autoimmune response to thyroglobulin in addition to the helper function that is necessary to initiate the autoimmune reaction.Entities:
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Year: 1975 PMID： 1079426 DOI： 10.1111/j.1749-6632.1975.tb29062.x
Source DB: PubMed Journal: Ann N Y Acad Sci ISSN： 0077-8923 Impact factor: 5.691