Literature DB >> 10793739

Unpaired bases in superhelical DNA: kinetic evidence.

R J Jacob, J Lebowitz, M P Printz.   

Abstract

Kinetic analysis of the early, fast reaction of superhelical DNA with formaldehyde reveals that this region or regions is 56% "single strand like" in character. Hydrogen-tritium exchange studies coupled with other considerations show that this reaction is not due to a difference in conformational motility between form I and form II molecules, but is due to unpaired or weakly hydrogen bonded, localized region(s) of the form I allomorph of circular DNA.

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Year:  1974        PMID： 10793739      PMCID： PMC343356          DOI： 10.1093/nar/1.4.549

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  13 in total

1.  A study of rapid hydrogen exchange in nucleic acids.

Authors:  C V Hanson
Journal:  J Mol Biol       Date:  1971-06-28       Impact factor: 5.469

2.  Hydrogen exchange as a probe of the dynamic structure of DNA. II. Effects of base composition and destabilizing salts.

Authors:  B McConnell; P H von Hippel
Journal:  J Mol Biol       Date:  1970-06-14       Impact factor: 5.469

3.  Interaction of closed circular DNA with intercalative dyes. II. The free energy of superhelix formation in SV40 DNA.

Authors:  W Bauer; J Vinograd
Journal:  J Mol Biol       Date:  1970-02-14       Impact factor: 5.469

4.  Further analysis of the altered secondary structure of superhelical DNA. Sensitivity to methylmercuric hydroxide a chemical probe for unpaired bases.

Authors:  T A Beerman; J Lebowitz
Journal:  J Mol Biol       Date:  1973-09-25       Impact factor: 5.469

5.  Dynamic aspects of native DNA structure: kinetics of the formaldehyde reaction with calf thymus DNA.

Authors:  P H Von Hippel; K Y Wong
Journal:  J Mol Biol       Date:  1971-11-14       Impact factor: 5.469

6.  On the kinetics of hydrogen exchange in deoxyribonucleic acid. pH and salt effects.

Authors:  M P Printz; P H von Hippel
Journal:  Biochemistry       Date:  1968-09       Impact factor: 3.162

Review 7.  Hydrogen exchange in proteins.

Authors:  A Hvidt; S O Nielsen
Journal:  Adv Protein Chem       Date:  1966

8.  Tritium-hydrogen exchange studies of polynucleotides. Double-stranded polyriboadenylic acid.

Authors:  M P Printz
Journal:  Biochemistry       Date:  1970-07-21       Impact factor: 3.162

9.  Hydrogen exchange as a probe of the dynamic structure of DNA. I. General acid-base catalysis.

Authors:  B McConnell; P H von Hippel
Journal:  J Mol Biol       Date:  1970-06-14       Impact factor: 5.469

10.  Kinetic studies of denaturation and reaction with formaldehyde on polydeoxyribonucleotides.

Authors:  H Utiyama; P Doty
Journal:  Biochemistry       Date:  1971-03-30       Impact factor: 3.162
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  7 in total

1.  An RNA fraction in chromatin of L-929 cells associated with DNA.

Authors:  J J Monahan; R H Hall
Journal:  Nucleic Acids Res       Date:  1974-11       Impact factor: 16.971

2.  Introduction of interrupted secondary structure in supercoiled DNA as a function of superhelix density: consideration of hairpin structures in superhelical DNA.

Authors:  M Woodworth-Gutai; J Lebowitz
Journal:  J Virol       Date:  1976-04       Impact factor: 5.103

3.  Carbodiimide modification of superhelical PM2 DNA: considerations regarding reaction at unpaired bases and the unwinding of superhelical DNA with chemical probes.

Authors:  J Lebowitz; A K Chaudhuri; A Gonenne; G Kitos
Journal:  Nucleic Acids Res       Date:  1977-06       Impact factor: 16.971

4.  Ultraviolet light irradiation of PM2 superhelical DNA.

Authors:  M Woodworth-Gutai; J Lebowitz; A C Kato; D T Denhardt
Journal:  Nucleic Acids Res       Date:  1977       Impact factor: 16.971

5.  Inhibition of transcription of supercoiled PM2 DNA by carbodiimide modification.

Authors:  M S Flashner; M A Katopes; J Lebowitz
Journal:  Nucleic Acids Res       Date:  1977-06       Impact factor: 16.971

6.  Extracellular nucleases of Alteromonas espejiana BAL 31.IV. The single strand-specific deoxyriboendonuclease activity as a probe for regions of altered secondary structure in negatively and positively supercoiled closed circular DNA.

Authors:  P P Lau; H B Gray
Journal:  Nucleic Acids Res       Date:  1979-01       Impact factor: 16.971

7.  Underwound DNA under tension: structure, elasticity, and sequence-dependent behaviors.

Authors:  Maxim Y Sheinin; Scott Forth; John F Marko; Michelle D Wang
Journal:  Phys Rev Lett       Date:  2011-09-01       Impact factor: 9.161
  7 in total

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