| Literature DB >> 10793662 |
S D Ehrlich, J P Thiery, A Devillers-Thiery, G Bernardi.
Abstract
The composition of the 3'terminal, 5'terminal and 5'penultimate nucleotides of the oligonucleotides released by spleen acid DNase and snail acid DNase from five ;repetitive' DNAs (guinea pig, mouse and crab satellite DNAs, yeast mitochondrial DNA and poly (dAT:dAT)) and four ;eukaryotic' DNAs (calf thymus, guinea pig and mouse liver DNAs, and yeast nuclear DNA) have been investigated and found to deviate in characteristic ways from those expected for bacterial DNAs having comparable base compositions. The deviation patterns obtained represent a novel way of characterizing and comparing different DNAs on the basis of the frequency of the nucleotide sequences they contain.Entities:
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Year: 1974 PMID: 10793662 PMCID: PMC343326 DOI: 10.1093/nar/1.1.87
Source DB: PubMed Journal: Nucleic Acids Res ISSN: 0305-1048 Impact factor: 16.971