Literature DB >> 10793659

Polynucleotides. XXII. Synthesis and properties of poly 7-deazainosinic acid.

M Ikehara, T Fukui, T Koide, J Inaba.   

Abstract

Poly 7-deazainosinic acid has been prepared by the deamination and phosphorylation of tubercidin and the nucleoside diphosphate was polymerised using polynucleotide phosphorylase. The polymer has similar physical properties to poly(I), but has a low thermal stability in the double-stranded complex with poly(C). Poly(7-deaza I), in contrast, forms a more stable triple-stranded complex with poly(A) than 2 poly(I). poly(A), presumably due to the higher pK value.

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Year:  1974        PMID： 10793659      PMCID： PMC343323          DOI： 10.1093/nar/1.1.53

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  9 in total

1.  [POLYNUCLEOTIDE PHOSPHORYLASE PURIFIED FROM ESCHERICHIA COLI].

Authors:  F R WILLIAMS; M GRUNBERG-MANAGO
Journal:  Biochim Biophys Acta       Date:  1964-07-08

2.  A displacement reaction between a polynucleotide Helix and a random coil.

Authors:  P B SIGLER; D R DAVIES; H T MILES
Journal:  J Mol Biol       Date:  1962-12       Impact factor: 5.469

3.  Polynucleotides. XI. Synthesis and properties of poly(2-methylinosinic acid).

Authors:  M Ikehara; M Hattori
Journal:  Biochim Biophys Acta       Date:  1972-06-22

4.  Inducers of interferon and host resistance, V. In vitro studies.

Authors:  A K Field; A A Tytell; G P Lampson; M R Hilleman
Journal:  Proc Natl Acad Sci U S A       Date:  1968-09       Impact factor: 11.205

5.  Synthesis and properties of poly(2-methylthioinosinic acid).

Authors:  M Ikehara; M Hattori
Journal:  Biochim Biophys Acta       Date:  1972-04-26

6.  Synthesis and properties of polyribonucleotides containing N 2 -methyl and N 2 -dimethylguanylic acid in polyguanylic acid.

Authors:  M Ikehara; M Hattori
Journal:  Biochemistry       Date:  1971-09-14       Impact factor: 3.162

7.  Some physical properties of poly 7-deazaadenylic acid (poly Tubercidin phosphoric acid).

Authors:  M Ikehara; T Fukui
Journal:  J Mol Biol       Date:  1968-12       Impact factor: 5.469

8.  Polynucleotides. XV. Synthesis and properties of polynucleotides containing N 2 -dimethylguanylic acid residues in polyinosinate and polyadenylate chains.

Authors:  M Ikehara; M Hattori
Journal:  Biochim Biophys Acta       Date:  1972-11-16

9.  Synthesis and coding properties of poly(c 1 A), poly(c 3 A), poly(c 7 A) and poly(h 6 A).

Authors:  L Hagenberg; H G Gassen; H Matthaei
Journal:  Biochem Biophys Res Commun       Date:  1973-02-20       Impact factor: 3.575
  9 in total
  3 in total

1.  Poly(adenylic acids) containing the antibiotic tubercidin -- base pairing and hydrolysis by nuclease S1.

Authors:  F Seela; J Ott; D Franzen
Journal:  Nucleic Acids Res       Date:  1982-02-25       Impact factor: 16.971

2.  Poly(2-methylthio-7-deazainosinic acid)--hydrophobic stabilization of polynucleotide secondary structure by the 2-methylthio group.

Authors:  F Seela; J Ott; D Franzen
Journal:  Nucleic Acids Res       Date:  1983-09-10       Impact factor: 16.971

3.  Role of purine N-3 in the biologic activities of poly(A) and poly(I).

Authors:  E de Clercq; P F Torrence; T Fukui; M Ikehara
Journal:  Nucleic Acids Res       Date:  1976-06       Impact factor: 16.971
  3 in total

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