Literature DB >> 10791044

[Myelomatous meningitis: a case report].

I Halczuk1, J Iłzecka, Z Stelmasiak.   

Abstract

Multiple myeloma is characterized by the production of a monoclonal immunoglobulin. Myelomatous meningitis is a rare occurrence in multiple myeloma. The signs of meningeal myelomatosis include impairment of consciousness, cranial nerve palsies, convulsions and plasmatic cells in the cerebrospinal fluid. Atypical, plasmatic cells in the cerebrospinal fluid are an important finding for the diagnosis of meningeal myeloma. A combination of radiation therapy and chemotherapy is the usual treatment. Patients with meningeal myelomatosis can have a good response to treatment initially, but their prognosis is poor and death occurs within a few months. We present the case of a woman with myelomatous meningitis. Multiple myeloma was diagnosed by serum protein electrophoresis and bone marrow aspiration. This case and a review of the literature show that clinical manifestations of meningeal myeloma are non-specific.

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Year:  1999        PMID: 10791044

Source DB:  PubMed          Journal:  Neurol Neurochir Pol        ISSN: 0028-3843            Impact factor:   1.621


  2 in total

1.  Progressive neurological deficits in multiple myeloma: meningeal myelomatosis without MRI abnormalities.

Authors:  S van Ginkel; T J Snijders; N W C J van de Donk; C J M Klijn; M L D Broekman
Journal:  J Neurol       Date:  2011-11-23       Impact factor: 4.849

2.  Multiple Cranial Nerve Palsy Concomitant with Leptomeningeal Involvement in Multiple Myeloma: A Case Report and Review of Literature.

Authors:  Neda Pak; Fatemeh Shakki Katouli; Amir Reza Radmard; Mohammad Hassan Shaki Katuli; Mohamad Mehdi Rezwanifar; Negar Sepehri Boroujeni
Journal:  Int J Hematol Oncol Stem Cell Res       Date:  2018-01-01
  2 in total

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