Literature DB >> 10790829

A finite element method for mechanical response of hair cell ciliary bundles.

J R Cotton1, J W Grant.   

Abstract

This paper describes the development of a methodology for performing a mechanical analysis of hair cell ciliary bundles. The cilia were modeled as shear deformable beams, and interconnections were modeled as two-force members. These models were incorporated into software, which performs a finite element analysis of a user-defined bundle. The algorithm incorporates aspects of the bundle such as geometric realignment and buckling of compressed side links. A sample bundle is introduced and results of modeling it are presented.

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Year:  2000        PMID: 10790829     DOI: 10.1115/1.429626

Source DB:  PubMed          Journal:  J Biomech Eng        ISSN: 0148-0731            Impact factor:   2.097


  11 in total

1.  Mechanical properties and consequences of stereocilia and extracellular links in vestibular hair bundles.

Authors:  Jong-Hoon Nam; John R Cotton; Ellengene H Peterson; Wally Grant
Journal:  Biophys J       Date:  2006-01-20       Impact factor: 4.033

2.  A virtual hair cell, II: evaluation of mechanoelectric transduction parameters.

Authors:  Jong-Hoon Nam; John R Cotton; Wally Grant
Journal:  Biophys J       Date:  2007-01-05       Impact factor: 4.033

3.  A virtual hair cell, I: addition of gating spring theory into a 3-D bundle mechanical model.

Authors:  Jong-Hoon Nam; John R Cotton; Wally Grant
Journal:  Biophys J       Date:  2007-01-05       Impact factor: 4.033

4.  The actions of calcium on hair bundle mechanics in mammalian cochlear hair cells.

Authors:  Maryline Beurg; Jong-Hoon Nam; Andrew Crawford; Robert Fettiplace
Journal:  Biophys J       Date:  2008-01-04       Impact factor: 4.033

5.  Theoretical conditions for high-frequency hair bundle oscillations in auditory hair cells.

Authors:  Jong-Hoon Nam; Robert Fettiplace
Journal:  Biophys J       Date:  2008-08-01       Impact factor: 4.033

Review 6.  Multiscale modeling of mechanotransduction in the utricle.

Authors:  Jong-Hoon Nam; J W Grant; M H Rowe; E H Peterson
Journal:  J Neurophysiol       Date:  2019-04-17       Impact factor: 2.714

7.  An operating principle of the turtle utricle to detect wide dynamic range.

Authors:  Jong-Hoon Nam
Journal:  Hear Res       Date:  2017-10-09       Impact factor: 3.208

8.  The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice.

Authors:  Jung-Bum Shin; Chantal M Longo-Guess; Leona H Gagnon; Katherine W Saylor; Rachel A Dumont; Kateri J Spinelli; James M Pagana; Phillip A Wilmarth; Larry L David; Peter G Gillespie; Kenneth R Johnson
Journal:  J Neurosci       Date:  2010-07-21       Impact factor: 6.167

9.  Underestimated sensitivity of mammalian cochlear hair cells due to splay between stereociliary columns.

Authors:  Jong-Hoon Nam; Anthony W Peng; Anthony J Ricci
Journal:  Biophys J       Date:  2015-06-02       Impact factor: 4.033

10.  Hair cell bundles: flexoelectric motors of the inner ear.

Authors:  Kathryn D Breneman; William E Brownell; Richard D Rabbitt
Journal:  PLoS One       Date:  2009-04-22       Impact factor: 3.240

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