Literature DB >> 10785416

Flavonol-cinnamate cycloadducts and diamide derivatives from Aglaia laxiflora.

Y J Xu1, X H Wu, B K Tan, Y H Lai, J J Vittal, Z Imiyabir, L Madani, K S Khozirah, S H Goh.   

Abstract

Leaf extracts of the Malaysian plant Aglaia laxiflora provided two cytotoxic compounds, a new rocaglaol rhamnoside (1), a known rocaglaol (2), new (but inactive) flavonol-cinnamaminopyrrolidine adducts (3-6), and their probable biosynthetic precursors (7 and trimethoxyflavonol). All structures were elucidated primarily by 2D NMR spectroscopy. The structure and stereochemistry of aglaxiflorin A (3) were confirmed by single-crystal X-ray crystallography.

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Year:  2000        PMID: 10785416     DOI: 10.1021/np990454d

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  5 in total

Review 1.  Chemistry and biology of rocaglamides (= flavaglines) and related derivatives from aglaia species (meliaceae).

Authors:  Sherif S Ebada; Neil Lajkiewicz; John A Porco; Min Li-Weber; Peter Proksch
Journal:  Prog Chem Org Nat Prod       Date:  2011

Review 2.  Rocaglamide, silvestrol and structurally related bioactive compounds from Aglaia species.

Authors:  Li Pan; John L Woodard; David M Lucas; James R Fuchs; A Douglas Kinghorn
Journal:  Nat Prod Rep       Date:  2014-05-02       Impact factor: 13.423

3.  Cytotoxic flavaglines and bisamides from Aglaia edulis.

Authors:  Soyoung Kim; Young-Won Chin; Bao-Ning Su; Soedarsono Riswan; Leonardus B S Kardono; Johar J Afriastini; Heebyung Chai; Norman R Farnsworth; Geoffrey A Cordell; Steven M Swanson; A Douglas Kinghorn
Journal:  J Nat Prod       Date:  2006-12       Impact factor: 4.050

4.  Bioactive flavaglines and other constituents isolated from Aglaia perviridis.

Authors:  Li Pan; Ulyana Muñoz Acuña; Jie Li; Nivedita Jena; Tran Ngoc Ninh; Caroline M Pannell; Heebyung Chai; James R Fuchs; Esperanza J Carcache de Blanco; Djaja D Soejarto; A Douglas Kinghorn
Journal:  J Nat Prod       Date:  2013-01-09       Impact factor: 4.050

5.  Total synthesis of (+)-grandiamide D, dasyclamide and gigantamide A from a Baylis-Hillman adduct: A unified biomimetic approach.

Authors:  Andivelu Ilangovan; Shanmugasundar Saravanakumar
Journal:  Beilstein J Org Chem       Date:  2014-01-10       Impact factor: 2.883

  5 in total

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