| Literature DB >> 10785410 |
O Thoison1, J Fahy, V Dumontet, A Chiaroni, C Riche, M V Tri, T Sévenet.
Abstract
Bioassay-guided fractionation of a leaf extract of G. bracteata has yielded six new prenylxanthones, bractatin (1), isobractatin (2), 1-O-methylbractatin (3), 1-O-methylisobractatin (4), 1-O-methyl-8-methoxy-8,8a-dihydrobractatin (5), and 1-O-methylneobractatin (6). The structures of these compounds have been elucidated by spectroscopic means (NMR, MS), literature data, and X-ray crystallographic analysis of 2. These compounds possess significant cytotoxicity against the KB cell line.Entities:
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Year: 2000 PMID： 10785410 DOI： 10.1021/np9903088
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050