Literature DB >> 10784440

Inhibition of cyclooxygenase-2 expression by diarylheptanoids from the bark of Alnus hirsuta var. sibirica.

M W Lee1, J H Kim, D W Jeong, K H Ahn, S H Toh, Y J Surh.   

Abstract

Two known diarylheptanoids, oregonin (1), (5S)-1,7-bis-(3,4-dihydroxyphenyl)-heptane-3-one-5-O-beta-D-xylopyranosi de and hirsutanonol (2), (5S)-1,7-bis-(3,4-dihydroxyphenyl)-5-hydroxyheptane-3-one isolated from the bark of Alnus hirsuta var. sibirica, showed significant inhibitory effects on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced cyclooxygenase-2 (COX-2) expression in immortalized human breast epithelial MCF10A cells.

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Year:  2000        PMID: 10784440     DOI: 10.1248/bpb.23.517

Source DB:  PubMed          Journal:  Biol Pharm Bull        ISSN: 0918-6158            Impact factor:   2.233


  8 in total

1.  Atopic dermatitis-like skin lesions reduced by topical application and intraperitoneal injection of Hirsutenone in NC/Nga mice.

Authors:  Mi Sook Jeong; Sun Eun Choi; Ji Young Kim; Jung Shim Kim; Eun Joo Kim; Kwan Hee Park; Do Ik Lee; Seong Soo Joo; Chung Soo Lee; Hyoweon Bang; Mi-Kyung Lee; Young Wook Choi; Kap-sok Li; Nam Ju Moon; Min Won Lee; Seong Jun Seo
Journal:  Clin Dev Immunol       Date:  2010-12-14

2.  Bioactive constituents and medicinal importance of genus Alnus.

Authors:  Sushil Chandra Sati; Nitin Sati; O P Sati
Journal:  Pharmacogn Rev       Date:  2011-07

3.  Phytochemical, antioxidant and hepatoprotective effects of Alnus nitida bark in carbon tetrachloride challenged Sprague Dawley rats.

Authors:  Moniba Sajid; Muhammad Rashid Khan; Naseer Ali Shah; Sayed Afzal Shah; Hammad Ismail; Tahira Younis; Zartash Zahra
Journal:  BMC Complement Altern Med       Date:  2016-08-03       Impact factor: 3.659

4.  Anti-oxidant and Anti-Inflammatory Cyclic Diarylheptanoids from Alnus japonica Stem Bark.

Authors:  Sabrin R M Ibrahim; Gamal A Mohamed; Amgad I M Khedr; Bader M Aljaeid
Journal:  Iran J Pharm Res       Date:  2017       Impact factor: 1.696

Review 5.  The Genus Alnus, A Comprehensive Outline of Its Chemical Constituents and Biological Activities.

Authors:  Xueyang Ren; Ting He; Yanli Chang; Yicheng Zhao; Xiaoyi Chen; Shaojuan Bai; Le Wang; Meng Shen; Gaimei She
Journal:  Molecules       Date:  2017-08-21       Impact factor: 4.411

6.  Anti-Inflammatory and Anti-Oxidative Activities of Phenolic Compounds from Alnus sibirica Stems Fermented by Lactobacillus plantarum subsp. argentoratensis.

Authors:  Thi Tam Le; Jun Yin; MinWon Lee
Journal:  Molecules       Date:  2017-09-18       Impact factor: 4.411

7.  Evaluation of Phytochemistry and Pharmacological Properties of Alnus nitida.

Authors:  Moniba Sajid; Muhammad Rashid Khan; Muhammad Umar Ijaz; Hammad Ismail; Muhammad Zeeshan Bhatti; Sayed Afzal Shah; Saima Ali; Muhammad Usman Tareen; Saqer S Alotaibi; Sarah M Albogami; Gaber El-Saber Batiha
Journal:  Molecules       Date:  2022-07-18       Impact factor: 4.927

Review 8.  Diarylheptanoids as nutraceutical: A review.

Authors:  G Ganapathy; R Preethi; J A Moses; C Anandharamakrishnan
Journal:  Biocatal Agric Biotechnol       Date:  2019-03-26
  8 in total

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