| Literature DB >> 10783981 |
D E Wedge1, J C Galindo, F A Macías.
Abstract
Fungicidal activity of 36 natural and synthetic sesquiterpene lactones with guaianolide, trans, trans-germacranolide, cis, cis-germacranolide, melampolide, and eudesmanolide carbon skeletons was evaluated against the phytopathogenic fungi Colletotrichum acutatum, C. fragariae, C. gloeosporioides, Fusarium oxysporum, Botrytis cinerea, and Phomopsis sp. Dose-response data for the active compounds dehydrozaluzanin C, dehydrocostuslactone, 5alpha-hydroxydehydrocostuslacone, costunolide, and zaluzanin C are presented. A new 96-well microbioassay procedure for fast and easy evaluation of antifungal activity was used to compare these compounds with commercial fungicide standards. Some structure-activity conclusions are also presented.Entities:
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Year: 2000 PMID： 10783981 DOI： 10.1016/s0031-9422(00)00008-x
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072