Literature DB >> 10782698

Synthesis and antifungal activity of a ferrocene-fluconazole analogue.

C Biot1, N François, L Maciejewski, J Brocard, D Poulain.   

Abstract

A novel ferrocene fluconazole analogue was synthesized and its antifungal properties investigated against yeast strains of medical importance, including those intrinsically resistant to fluconazole. In vitro tests revealed a slight increase in fungal growth and a reversal of the effect of fluconazole at minimal inhibitory concentrations.

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Year:  2000        PMID： 10782698     DOI： 10.1016/s0960-894x(00)00120-7

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  4 in total

1.  Aminequinone-hydroxylquinoneimine tautomeric equilibrium revisited: molecular modeling study of the tautomeric equilibrium and substituent effects in 4-(4-R-phenylamino)naphthalene-1,2-diones.

Authors:  Thaís P Fragoso; José Walkimar de Mesquita Carneiro; Maria D Vargas
Journal:  J Mol Model       Date:  2009-09-13       Impact factor: 1.810

2.  Synthesis, characterization, and antimicrobial evaluation of a small library of ferrocene-containing acetoacetates and phenyl analogs: the discovery of a potent anticandidal agent.

Authors:  Niko S Radulović; Marko Z Mladenović; Zorica Stojanović-Radić; Goran A Bogdanović; Dragana Stevanović; Rastko D Vukićević
Journal:  Mol Divers       Date:  2014-03-13       Impact factor: 2.943

3.  Synthesis, characterization, and antimicrobial evaluation of carbostyril derivatives of 1H-pyrazole.

Authors:  Nilesh J Thumar; Manish P Patel
Journal:  Saudi Pharm J       Date:  2011-02-03       Impact factor: 4.330

4.  Synthesis and biological evaluation of Schiff bases and azetidinones of 1-naphthol.

Authors:  Sushil Kumar; Punit Kumar; Nitin Sati
Journal:  J Pharm Bioallied Sci       Date:  2012-07
  4 in total

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