| Literature DB >> 10782680 |
H Chávez1, G Rodríguez, A Estévez-Braun, A G Ravelo, R Estévez-Reyes, A G González, J L Fdez-Puente, D García-Grávalos.
Abstract
Macrocarpins A (1), B (2), C (3) and D (4), four new nor-triterpenes, have been isolated from the roots of Maytenus macrocarpa. The structures were established by spectroscopic examinations. Natural compounds 1, 2, 4 and the acetyl derivative 1a are cytotoxic against four tumoral cell lines with IC50 values ranging between 0.4 and 5.2 microM.Entities:
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Year: 2000 PMID： 10782680 DOI： 10.1016/s0960-894x(00)00082-2
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823