Literature DB >> 10782668

Suitably functionalised pyrimidines as potential antimycotic agents.

N Agarwal1, S K Raghuwanshi, D N Upadhyay, P K Shukla, V J Ram.   

Abstract

Various suitably functionalized pyrimidine derivatives have been synthesized to explore their potential as antimycotic agents. Some of the synthesized compounds 4c, 4d, 8a-e have shown highly significant in vitro antifungal activity against five human pathogenic fungi.

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Year:  2000        PMID： 10782668     DOI： 10.1016/s0960-894x(00)00091-3

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  8 in total

Review 1.  Research developments in the syntheses, anti-inflammatory activities and structure-activity relationships of pyrimidines.

Authors:  Haroon Ur Rashid; Marco Antonio Utrera Martines; Adriana Pereira Duarte; Juliana Jorge; Shagufta Rasool; Riaz Muhammad; Nasir Ahmad; Muhammad Naveed Umar
Journal:  RSC Adv       Date:  2021-02-03       Impact factor: 3.361

2.  Structural and theoretical studies of 4-chloro-2-methyl-6-oxo-3,6-dideuteropyrimidin-1-ium chloride (d 6).

Authors:  Ray J Butcher; Andrew P Purdy; Sean A Fischer; Daniel Gunlycke
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2021-03-19

3.  Antimicrobial evaluation of novel substituted pyrimidinopyrazoles and pyrimidinotriazoles.

Authors:  H S Basavaraja; J E Nagamani; M M J Vijay Kumar; Basavaraj Padmashali
Journal:  J Adv Pharm Technol Res       Date:  2010-04

Review 4.  Significance and biological importance of pyrimidine in the microbial world.

Authors:  Vinita Sharma; Nitin Chitranshi; Ajay Kumar Agarwal
Journal:  Int J Med Chem       Date:  2014-03-23

5.  Pyrimidine-5-carbonitrile based potential anticancer agents as apoptosis inducers through PI3K/AKT axis inhibition in leukaemia K562.

Authors:  Nehad M El-Dydamony; Rana M Abdelnaby; Rasha Abdelhady; Omaima Ali; Mohamed I Fahmy; Rasha R Fakhr Eldeen; Amira A Helwa
Journal:  J Enzyme Inhib Med Chem       Date:  2022-12       Impact factor: 5.051

6.  Structural Insights of Three 2,4-Disubstituted Dihydropyrimidine-5-carbonitriles as Potential Dihydrofolate Reductase Inhibitors.

Authors:  Lamya H Al-Wahaibi; Althaf Shaik; Mohammed A Elmorsy; Mohammed S M Abdelbaky; Santiago Garcia-Granda; Subbiah Thamotharan; Vijay Thiruvenkatam; Ali A El-Emam
Journal:  Molecules       Date:  2021-05-29       Impact factor: 4.411

7.  Synthesis, antifungal activity, and QSAR studies of 1,6-dihydropyrimidine derivatives.

Authors:  Chirag Rami; Laxmanbhai Patel; Chhaganbhai N Patel; Jayshree P Parmar
Journal:  J Pharm Bioallied Sci       Date:  2013-10

8.  Naturally Inspired Pyrimidines Analogues for Alzheimer's Disease.

Authors:  Shivani Singh; Meenakshi Dhanawat; Sumeet Gupta; Deepak Kumar; Saloni Kakkar; Anroop Nair; Inderjeet Verma; Prerna Sharma
Journal:  Curr Neuropharmacol       Date:  2021       Impact factor: 7.363
  8 in total

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