Literature DB >> 10781408

Functional dissection of BCR signaling pathways.

T Kurosaki1.   

Abstract

Signal transduction by the BCR is critical for progression through developmental checkpoints as well as for immune responses. Recent results obtained in mice deficient either in an adaptor molecule, BLNK (alternatively named SLP-65 or BASH), or in phosphatidylinositol 3-kinase have revealed similar - though not identical - phenotypes to those of Btk(-/-) mice, suggesting a functional link between BLNK, Btk and phosphatidylinositol 3-kinase.

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Year:  2000        PMID: 10781408     DOI: 10.1016/s0952-7915(00)00087-x

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN: 0952-7915            Impact factor:   7.486


  27 in total

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9.  The protein-tyrosine kinase Syk interacts with TRAF-interacting protein TRIP in breast epithelial cells.

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