Literature DB >> 10781404

Adapter proteins in lymphocyte antigen-receptor signaling.

P S Myung1, N J Boerthe, G A Koretzky.   

Abstract

Adapter molecules contain discrete modular domains that direct specific intermolecular interactions to orchestrate assembly of signaling complexes. A number of adapter proteins play critical roles in both positive and negative regulation of antigen-receptor signaling, influencing lymphocyte development and function.

Mesh：

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Year:  2000        PMID： 10781404     DOI： 10.1016/s0952-7915(00)00085-6

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  29 in total

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Review 7.  Biochemical signaling pathways for memory T cell recall.

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10.  Studies of a germinal centre B-cell expressed gene, GCET2, suggest its role as a membrane associated adapter protein.

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