Literature DB >> 10780793

Eosinophils are neither migrated nor activated in the skin lesions of atopic dermatitis in infants.

N Kondo1, S Shinoda, O Fukutomi, H Agata, T Terada, H Shikano, A M Montaño, H Sakaguchi, M Watanabe, K Komiyama, Y Yokoyama, N Morimoto.   

Abstract

Eosinophils and eosinophil cationic protein (ECP) were examined in the skin lesions of 10 infants with atopic dermatitis (aged 4 months to 7 years). In all 10 patients, neutrophils and eosinophils were rarely seen in these lesions. Moreover, in the immunohistochemical study, ECP was scarcely detected in any of them. Our results suggest that eosinophils are neither migrated nor activated in the skin in atopic dermatitis in infants.

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Year:  2000        PMID: 10780793

Source DB:  PubMed          Journal:  J Investig Allergol Clin Immunol        ISSN: 1018-9068            Impact factor:   4.333


  1 in total

1.  Eosinophil ribonucleases and their cutaneous lesion-forming activity.

Authors:  Douglas A Plager; Mark D P Davis; Amy G Andrews; Michael J Coenen; Terry J George; Gerald J Gleich; Kristin M Leiferman
Journal:  J Immunol       Date:  2009-08-28       Impact factor: 5.422

  1 in total

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