| Literature DB >> 10780395 |
N Sugimoto1, N Satoh, K Yamamoto.
Abstract
We have examined quantitatively stabilities of PNA/DNA hybrid duplexes with identical nearest-neighbor base pairs and compared stabilities between PNA/DNA and DNA/DNA. The average difference of stabilization energy of the short PNA/DNA was 0.9 kcal mol(-1), which suggests that the stability of the hybrids with identical nearest-neighbor base pairs can be predicted with the nearest-neighbor model as well as those of nucleic acid duplexes.Mesh:
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Year: 1999 PMID: 10780395 DOI: 10.1093/nass/42.1.93
Source DB: PubMed Journal: Nucleic Acids Symp Ser ISSN: 0261-3166