Literature DB >> 10780395

Comparison of thermodynamic stabilities between PNA (peptide nucleic acid)/DNA hybrid duplexes and DNA/DNA duplexes.

N Sugimoto1, N Satoh, K Yamamoto.   

Abstract

We have examined quantitatively stabilities of PNA/DNA hybrid duplexes with identical nearest-neighbor base pairs and compared stabilities between PNA/DNA and DNA/DNA. The average difference of stabilization energy of the short PNA/DNA was 0.9 kcal mol(-1), which suggests that the stability of the hybrids with identical nearest-neighbor base pairs can be predicted with the nearest-neighbor model as well as those of nucleic acid duplexes.

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Year:  1999        PMID: 10780395     DOI: 10.1093/nass/42.1.93

Source DB:  PubMed          Journal:  Nucleic Acids Symp Ser        ISSN: 0261-3166


  3 in total

1.  Detection of BCR-ABL T315I mutation by peptide nucleic acid directed PCR clamping and by peptide nucleic acid FISH.

Authors:  Valentina Rosso; Enrico Bracco; Roberto Pedrola; Sonia Carturan; Elisabetta Signorino; Jessica Petiti; Chiara Calabrese; Paolo Nicoli; Marco De Gobbi; Valentina Gaidano; Daniela Gallo; Stefano Ulisciani; Carmen Fava; Giovanna Rege-Cambrin; Francesco Frassoni; Giuseppe Saglio; Daniela Cilloni
Journal:  Biomark Res       Date:  2015-07-03

2.  A novel assay to detect calreticulin mutations in myeloproliferative neoplasms.

Authors:  Valentina Rosso; Jessica Petiti; Enrico Bracco; Roberto Pedrola; Francesca Carnuccio; Elisabetta Signorino; Sonia Carturan; Chiara Calabrese; Giada Bot-Sartor; Michela Ronconi; Anna Serra; Giuseppe Saglio; Francesco Frassoni; Daniela Cilloni
Journal:  Oncotarget       Date:  2017-01-24

3.  Design and application of a novel PNA probe for the detection at single cell level of JAK2V617F mutation in Myeloproliferative Neoplasms.

Authors:  Enrico Bracco; Valentina Rosso; Anna Serra; Francesca Carnuccio; Valentina Gaidano; Paolo Nicoli; Pellegrino Musto; Giuseppe Saglio; Francesco Frassoni; Daniela Cilloni
Journal:  BMC Cancer       Date:  2013-07-18       Impact factor: 4.430

  3 in total

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