Literature DB >> 10779412

Antagonists of protein-protein interactions.

A G Cochran1.   

Abstract

Protein-protein interactions are often attractive, but not straightforward, targets for disease therapy. Two strategies for identifying inhibitors of these interactions, peptide phage display and high-throughput screening, have recently shown new promise.

Mesh：

Substances：

Year:  2000        PMID： 10779412     DOI： 10.1016/s1074-5521(00)00106-x

Source DB:  PubMed          Journal:  Chem Biol        ISSN： 1074-5521


  54 in total

1.  Modulation of protein-protein interactions by synthetic receptors: design of molecules that disrupt serine protease-proteinaceous inhibitor interaction.

Authors:  Hyung Soon Park; Qing Lin; Andrew D Hamilton
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-16       Impact factor: 11.205

2.  Protein-protein interaction panel using mouse full-length cDNAs.

Authors:  H Suzuki; Y Fukunishi; I Kagawa; R Saito; H Oda; T Endo; S Kondo; H Bono; Y Okazaki; Y Hayashizaki
Journal:  Genome Res       Date:  2001-10       Impact factor: 9.043

3.  Chemically programmed monoclonal antibodies for cancer therapy: adaptor immunotherapy based on a covalent antibody catalyst.

Authors:  Christoph Rader; Subhash C Sinha; Mikhail Popkov; Richard A Lerner; Carlos F Barbas
Journal:  Proc Natl Acad Sci U S A       Date:  2003-04-17       Impact factor: 11.205

4.  Structural view of a fungal toxin acting on a 14-3-3 regulatory complex.

Authors:  Martin Würtele; Christian Jelich-Ottmann; Alfred Wittinghofer; Claudia Oecking
Journal:  EMBO J       Date:  2003-03-03       Impact factor: 11.598

5.  Short constrained peptides that inhibit HIV-1 entry.

Authors:  Samuel K Sia; Peter A Carr; Andrea G Cochran; Vladimir N Malashkevich; Peter S Kim
Journal:  Proc Natl Acad Sci U S A       Date:  2002-11-04       Impact factor: 11.205

6.  Molecular recognition of protein surfaces: high affinity ligands for the CBP KIX domain.

Authors:  Stacey E Rutledge; Heather M Volkman; Alanna Schepartz
Journal:  J Am Chem Soc       Date:  2003-11-26       Impact factor: 15.419

7.  Design and synthesis of type-III mimetics of omega-conotoxin GVIA.

Authors:  J B Baell; S A Forsyth; R W Gable; R S Norton; R J Mulder
Journal:  J Comput Aided Mol Des       Date:  2001-12       Impact factor: 3.686

8.  Protein grafting of an HIV-1-inhibiting epitope.

Authors:  Samuel K Sia; Peter S Kim
Journal:  Proc Natl Acad Sci U S A       Date:  2003-08-11       Impact factor: 11.205

9.  Selective inhibition of calcineurin-NFAT signaling by blocking protein-protein interaction with small organic molecules.

Authors:  Michael H A Roehrl; Sunghyun Kang; José Aramburu; Gerhard Wagner; Anjana Rao; Patrick G Hogan
Journal:  Proc Natl Acad Sci U S A       Date:  2004-05-06       Impact factor: 11.205

Review 10.  Understanding protein non-folding.

Authors:  Vladimir N Uversky; A Keith Dunker
Journal:  Biochim Biophys Acta       Date:  2010-02-01
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