Literature DB >> 10777834

Prenatal ages and stages-measures and errors.

R O'Rahilly1, F Müller.   

Abstract

BACKGROUND: The confusing term "gestational age" is generally either not defined or is used for menstrual "age," postovulatory age, or postfertilizational age. The designation (post)menstrual weeks and/or days is very useful in obstetrics but, because prenatal age extends from fertilization to birth, menstrual "age" is a misnomer. The term "stage" has a specific morphological meaning in embryology and should not be used either for ages or for lengths.
METHODS: Embryonic age is best assessed, when possible, from the 23 internationally recognized morphological stages. A morphological staging system is not available for the fetal period, and fetal age is assessed mainly from measurements.
RESULTS: Among these, the unsatisfactory designation crown-rump length (CRL) should be replaced, in ultrasonic biometry as well as in embryology, by the greatest length (GL), exclusive of the lower limbs. These points are discussed in detail, and justification for the views expressed is provided.
CONCLUSIONS: The continuing confusion concerning prenatal age is shown to be unnecessary once the ambiguous and superfluous term "gestational age" is abandoned. Copyright 2000 Wiley-Liss, Inc.

Mesh:

Year:  2000        PMID: 10777834     DOI: 10.1002/(SICI)1096-9926(200005)61:5<382::AID-TERA10>3.0.CO;2-5

Source DB:  PubMed          Journal:  Teratology        ISSN: 0040-3709


  6 in total

1.  Segmentation in staged human embryos: the occipitocervical region revisited.

Authors:  Fabiola Müller; Ronan O'Rahilly
Journal:  J Anat       Date:  2003-09       Impact factor: 2.610

2.  The amygdaloid complex and the medial and lateral ventricular eminences in staged human embryos.

Authors:  Fabiola Müller; Ronan O'Rahilly
Journal:  J Anat       Date:  2006-05       Impact factor: 2.610

3.  The development of the neural crest in the human.

Authors:  Ronan O'Rahilly; Fabiola Müller
Journal:  J Anat       Date:  2007-09       Impact factor: 2.610

Review 4.  When Does the Human Embryonic Heart Start Beating? A Review of Contemporary and Historical Sources of Knowledge about the Onset of Blood Circulation in Man.

Authors:  Jörg Männer
Journal:  J Cardiovasc Dev Dis       Date:  2022-06-09

5.  Dependency of magnetocardiographically determined fetal cardiac time intervals on gestational age, gender and postnatal biometrics in healthy pregnancies.

Authors:  Peter Van Leeuwen; Silke Lange; Anita Klein; Daniel Geue; Dietrich HW Grönemeyer
Journal:  BMC Pregnancy Childbirth       Date:  2004-04-02       Impact factor: 3.007

6.  Transvaginal three-dimensional sonographic assessment of the embryonic brain: a pilot study.

Authors:  Dan Boitor-Borza; Tunde Kovacs; Florin Stamatian
Journal:  Clujul Med       Date:  2015-04-15
  6 in total

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