Literature DB >> 10775778

Pre- or postnatal testosterone and flutamide effects on sexually dimorphic nuclei of the rat hypothalamus.

T D Lund1, D L Salyer, D E Fleming, E D Lephart.   

Abstract

Utilizing the sexually dimorphic nature of hypothalamic nuclei, a determination of the effects of pre- or postnatal flutamide and testosterone treatments were examined in male and female rats. Statistical analysis compared treatments, sex, and time of injection in terms of the sexually dimorphic nucleus of the preoptic area (SDN-POA) and the anteroventral periventricular nucleus (AVPV) volumes and lengths. The present findings establish that pre- or postnatal hormonal environments are crucial in influencing sexual morphology on the developing brain.

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Year:  2000        PMID: 10775778     DOI: 10.1016/s0165-3806(00)00013-4

Source DB:  PubMed          Journal:  Brain Res Dev Brain Res        ISSN: 0165-3806


  11 in total

Review 1.  Androgens, aging, and Alzheimer's disease.

Authors:  Christian J Pike; Emily R Rosario; Thuy-Vi V Nguyen
Journal:  Endocrine       Date:  2006-04       Impact factor: 3.633

Review 2.  Neuroendocrine consequences of androgen excess in female rodents.

Authors:  Eileen M Foecking; Melissa A McDevitt; Maricedes Acosta-Martínez; Teresa H Horton; Jon E Levine
Journal:  Horm Behav       Date:  2008-01-10       Impact factor: 3.587

3.  Androgens Mediate Sex-Dependent Gonadotropin Expression During Late Prenatal Development in the Mouse.

Authors:  Michael J Kreisman; Christopher I Song; Kathleen Yip; Bryony V Natale; David R Natale; Kellie M Breen
Journal:  Endocrinology       Date:  2017-09-01       Impact factor: 4.736

4.  The androgen 5alpha-dihydrotestosterone and its metabolite 5alpha-androstan-3beta, 17beta-diol inhibit the hypothalamo-pituitary-adrenal response to stress by acting through estrogen receptor beta-expressing neurons in the hypothalamus.

Authors:  Trent D Lund; Laura R Hinds; Robert J Handa
Journal:  J Neurosci       Date:  2006-02-01       Impact factor: 6.167

5.  Blockade of androgen receptors is sufficient to alter the sexual differentiation of the substantia nigra pars reticulata seizure-controlling network.

Authors:  James G Heida; Jana Velísková; Solomon L Moshé
Journal:  Epileptic Disord       Date:  2008-03       Impact factor: 1.819

Review 6.  A role for the androgen receptor in the sexual differentiation of the olfactory system in mice.

Authors:  Cristian Bodo
Journal:  Brain Res Rev       Date:  2007-09-05

Review 7.  Androgen regulation of beta-amyloid protein and the risk of Alzheimer's disease.

Authors:  Emily R Rosario; Christian J Pike
Journal:  Brain Res Rev       Date:  2007-07-07

8.  The androgen receptor is selectively involved in organization of sexually dimorphic social behaviors in mice.

Authors:  Cristian Bodo; Emilie F Rissman
Journal:  Endocrinology       Date:  2008-05-08       Impact factor: 4.736

Review 9.  Androgen cell signaling pathways involved in neuroprotective actions.

Authors:  Christian J Pike; Thuy-Vi V Nguyen; Martin Ramsden; Mingzhong Yao; M Paul Murphy; Emily R Rosario
Journal:  Horm Behav       Date:  2007-11-22       Impact factor: 3.587

10.  Neuronal nitric oxide synthase and calbindin delineate sex differences in the developing hypothalamus and preoptic area.

Authors:  Michelle Edelmann; Cory Wolfe; Elka M Scordalakes; Emilie F Rissman; Stuart Tobet
Journal:  Dev Neurobiol       Date:  2007-09-01       Impact factor: 3.964

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