| Literature DB >> 10772606 |
J R Hughes1, J A Grass, J L Pillitteri.
Abstract
A growing proportion of smokers are those who have failed prior treatments for cessation. We tested the efficacy of nicotine nasal spray and nicotine inhaler in two uncontrolled, open-label studies of 19 and 20 smokers who had previously failed nicotine patch therapy. As in the three prior studies of treatment failures, 6 month abstinence rates were extremely low both with the nasal spray (0%) and the inhaler (5%). We discuss possible treatments for and methodological issues in researching treatment-resistant smokers.Entities:
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Year: 2000 PMID： 10772606 DOI： 10.1300/J069v19n01_08
Source DB: PubMed Journal: J Addict Dis ISSN： 1055-0887