Literature DB >> 10772305

Limitations of magnetic resonance imaging in the evaluation of perineural tumor spread causing facial nerve paralysis.

M Jungehuelsing1, C Sittel, R Fischbach, M Wagner, E Stennert.   

Abstract

OBJECTIVE: To present and discuss the clinical presentation and treatment in patients with long-duration unilateral facial paralysis and normal magnetic resonance imaging (MRI) findings.
DESIGN: Case series.
SETTING: Ear, nose, and throat department of the University of Cologne, Cologne, Germany. PATIENTS: A total of 486 patients with unilateral facial paralysis who were treated from 1986 to 1998. Besides the usual diagnostic workup, a complete electrophysiological evaluation, including investigations such as needle electromyography and neuromyography (also known as electroneurography), of the facial nerve was performed at repeated intervals. In 19 patients, a malignant tumor was delineated with ultrasonography or MRI. In 8 of these patients, the initially performed MRI did not detect any parotid gland lesion causing the paralysis, whereas long duration of the paralysis and electroneurography indicated malignancy.
RESULTS: Exploration surgery was performed as total parotidectomy in these 8 patients and malignant parotid gland tumors were proved in all 8 patients.
CONCLUSIONS: Individuals with facial nerve paralysis without any signs of regeneration 6 months after the onset of paralysis and/or persistent electrophysiological evidence of ongoing neuronal degeneration should undergo surgical exploration of the parotid gland and facial nerve, even if MRI studies show no tumoral lesion.

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Year:  2000        PMID: 10772305     DOI: 10.1001/archotol.126.4.506

Source DB:  PubMed          Journal:  Arch Otolaryngol Head Neck Surg        ISSN: 0886-4470


  13 in total

1.  [Diagnostics of diseases and the function of the facial nerve].

Authors:  O Guntinas-Lichius; C Sittel
Journal:  HNO       Date:  2004-12       Impact factor: 1.284

Review 2.  Salivary acinic cell carcinoma: reappraisal and update.

Authors:  V Vander Poorten; A Triantafyllou; L D R Thompson; J Bishop; E Hauben; J Hunt; A Skalova; G Stenman; R P Takes; D R Gnepp; H Hellquist; B Wenig; D Bell; A Rinaldo; A Ferlito
Journal:  Eur Arch Otorhinolaryngol       Date:  2015-12-19       Impact factor: 2.503

Review 3.  [Cerebral nerves - perineural tumor spread].

Authors:  S Bisdas; M G Mack
Journal:  Radiologe       Date:  2009-07       Impact factor: 0.635

4.  Parotid carcinoma: Current diagnostic workup and treatment.

Authors:  Vincent L M Vander Poorten; Francis Marchal; Sandra Nuyts; Paul M J Clement
Journal:  Indian J Surg Oncol       Date:  2010-11-21

5.  [Facial nerve palsy due to a benign parotid gland tumor].

Authors:  M Grosheva; M Ortmann; D Beutner
Journal:  HNO       Date:  2010-12       Impact factor: 1.284

Review 6.  A systematic review of the incidence of basal cell carcinoma with perineural invasion: conventional pathology versus Mohs micrographic surgery.

Authors:  Madison J Hill; Karl M Hoegler; Albert E Zhou; Chloe R Snow; Amor Khachemoune
Journal:  Arch Dermatol Res       Date:  2022-04-25       Impact factor: 3.017

7.  Facial Palsy, Radiographic and Other Workup Negative: FROWN.

Authors:  Jacqueline J Greene; Reza Sadjadi; Nate Jowett; Tessa Hadlock
Journal:  Neurol Clin Pract       Date:  2021-10

8.  Bell's palsy misdiagnosis: characteristics of occult tumors causing facial paralysis.

Authors:  Eun-Jae Chung; Damir Matic; Kevin Fung; S Danielle MacNeil; Anthony C Nichols; Ruba Kiwan; KengYeow Tay; John Yoo
Journal:  J Otolaryngol Head Neck Surg       Date:  2022-10-18

9.  Imaging findings in craniofacial childhood rhabdomyosarcoma.

Authors:  Nicole J M Freling; Johannes H M Merks; Peerooz Saeed; Alfons J M Balm; Johannes Bras; Bradley R Pieters; Judit A Adam; Rick R van Rijn
Journal:  Pediatr Radiol       Date:  2010-08-20

Review 10.  Review of Perineural Invasion in Keratinocyte Carcinomas.

Authors:  Albert E Zhou; Karl M Hoegler; Amor Khachemoune
Journal:  Am J Clin Dermatol       Date:  2021-06-08       Impact factor: 7.403

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