| Literature DB >> 10769016 |
P Kern1, M Dietrich, C Hemmer, N Wellinghausen.
Abstract
Levels of soluble Fas ligand (sFasL) in serum were elevated in patients with Plasmodium falciparum malaria and showed a significant decline during disease course. sFasL levels that were elevated before antimalarial treatment began correlated significantly with depressed total lymphocyte and T-cell counts. These data suggest that Fas-induced apoptosis might play a role in malaria-associated lymphopenia.Entities:
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Year: 2000 PMID: 10769016 PMCID: PMC97531 DOI: 10.1128/IAI.68.5.3061-3063.2000
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441