Literature DB >> 10768179

Total synthesis of fully acetylated N-acetylneuraminic acid (Neu5Ac), 2-deoxy-beta-Neu5Ac, and 4-epi-2-deoxy-beta-Neu5Ac from D-glucose

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Abstract

Sialic acid and its analogues have been synthesized using a salenCo(II) complex catalyzed hetero Diels-Alder reaction and oxidative azidation (CAN/NaN3) of silyl enol ether as the key steps.

Entities:  

Year:  2000        PMID： 10768179     DOI： 10.1021/ol0055418

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  1 in total

1.  Chemo-enzymatic synthesis of the carbohydrate antigen N-glycolylneuraminic acid from glucose.

Authors:  Oliver M T Pearce; Ajit Varki
Journal:  Carbohydr Res       Date:  2010-04-09       Impact factor: 2.104
  1 in total

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