Literature DB >> 10766068

Osteoinductive bone graft substitutes.

S C Ludwig1, J M Kowalski, S D Boden.   

Abstract

This review will summarize the major efforts currently underway to develop osteoinductive bone graft substitutes for minimally invasive spine fusions. The primary categories of substitute include purified bone growth factors, recombinant bone growth factors, and growth factors delivered by gene therapy approaches. Clinical trials are underway for the purified and recombinant bone growth factors and pre-clinical studies have yielded promising results for a variety of gene therapy techniques for generating bone.

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Year:  2000        PMID： 10766068      PMCID： PMC3611431          DOI： 10.1007/pl00008317

Source DB:  PubMed          Journal:  Eur Spine J        ISSN： 0940-6719            Impact factor:   3.134


  9 in total

1.  Ex vivo transfer of the Hoxc-8-interacting domain of Smad1 by a tropism-modified adenoviral vector results in efficient bone formation in a rabbit model of spinal fusion.

Authors:  Joanne T Douglas; Angel A Rivera; Gray R Lyons; Patricia F Lott; Dezhi Wang; Majd Zayzafoon; Gene P Siegal; Xu Cao; Steven M Theiss
Journal:  J Spinal Disord Tech       Date:  2010-02

2.  Static Versus Expandable Devices Provide Similar Clinical Outcomes Following Minimally Invasive Transforaminal Lumbar Interbody Fusion.

Authors:  Benjamin Khechen; Brittany E Haws; Dil V Patel; Joon S Yoo; Jordan A Guntin; Kaitlyn L Cardinal; Sravisht Iyer; Kern Singh
Journal:  HSS J       Date:  2019-03-27

Review 3.  Improving the clinical evidence of bone graft substitute technology in lumbar spine surgery.

Authors:  Wellington K Hsu; M S Nickoli; J C Wang; J R Lieberman; H S An; S T Yoon; J A Youssef; D S Brodke; C M McCullough
Journal:  Global Spine J       Date:  2012-10-09

Review 4.  Bone substitutes in orthopaedic surgery: from basic science to clinical practice.

Authors:  V Campana; G Milano; E Pagano; M Barba; C Cicione; G Salonna; W Lattanzi; G Logroscino
Journal:  J Mater Sci Mater Med       Date:  2014-05-28       Impact factor: 3.896

5.  Osteogenic properties of PBLG-g-HA/PLLA nanocomposites.

Authors:  Lan Liao; Shuang Yang; Richard J Miron; Junchao Wei; Yufeng Zhang; Meng Zhang
Journal:  PLoS One       Date:  2014-09-03       Impact factor: 3.240

6.  Comparison of rhBMP-2 versus Autogenous Iliac Crest Bone Graft for 2-Level Anterior Cervical Discectomy and Fusion for Cervical Spondylotic Myelopathy.

Authors:  Bingyi Tan; Haiyan Wang; Jun Dong; Zenong Yuan; Dachuan Wang; Feng Wang
Journal:  Med Sci Monit       Date:  2015-10-19

7.  Topography of calcium phosphate ceramics regulates primary cilia length and TGF receptor recruitment associated with osteogenesis.

Authors:  Jingwei Zhang; Melis T Dalbay; Xiaoman Luo; Erik Vrij; Davide Barbieri; Lorenzo Moroni; Joost D de Bruijn; Clemens A van Blitterswijk; J Paul Chapple; Martin M Knight; Huipin Yuan
Journal:  Acta Biomater       Date:  2017-04-27       Impact factor: 8.947

8.  Fusion Rates of Lateral Lumbar Interbody Fusion Using Recombinant Human Bone Morphogenetic Protein-2.

Authors:  Ardalan A Nourian; Justin Harrington; Pamela A Pulido; Julie C McCauley; James D Bruffey; Robert K Eastlack
Journal:  Global Spine J       Date:  2018-09-25

Review 9.  Immunomodulation Effect of Biomaterials on Bone Formation.

Authors:  Tong Zhao; Zhuangzhuang Chu; Jun Ma; Liping Ouyang
Journal:  J Funct Biomater       Date:  2022-07-25
  9 in total

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