BACKGROUND: Adenoid cystic carcinoma is an uncommon tumor of the salivary gland. Little has been published on the chemotherapy of this neoplasm. METHODS: The literature on this disease is reviewed, and data from seven unpublished cases are presented. RESULTS: Four patients received cyclophosphamide. One responded, and another had pain relief. The literature review did not identify any single drug or combination that might be regarded as the treatment of choice. CONCLUSIONS: Systematic, multi-institutional studies are required to determine appropriate systemic treatment for metastatic adenoid cystic carcinoma of salivary gland origin.
BACKGROUND:Adenoid cystic carcinoma is an uncommon tumor of the salivary gland. Little has been published on the chemotherapy of this neoplasm. METHODS: The literature on this disease is reviewed, and data from seven unpublished cases are presented. RESULTS: Four patients received cyclophosphamide. One responded, and another had pain relief. The literature review did not identify any single drug or combination that might be regarded as the treatment of choice. CONCLUSIONS: Systematic, multi-institutional studies are required to determine appropriate systemic treatment for metastatic adenoid cystic carcinoma of salivary gland origin.
Authors: Othman Bin-Alamer; Ali S Haider; Adhiraj Chaudhary; Kishore Balasubramanian; Tessa Breeding; Paolo Palmisciano; Maryam Haider; Aaron A Cohen-Gadol; Tarek Y El Ahmadieh; Kenny Yu Journal: Cancer Diagn Progn Date: 2022-09-03
Authors: Danyel Elias da Cruz Perez; José Magrin; Oslei Paes de Almeida; Luiz Paulo Kowalski Journal: Pathol Oncol Res Date: 2007-07-03 Impact factor: 3.201
Authors: Ilias Karasmanis; John K Goudakos; Iosif Vital; Thomas Zarampoukas; Victor Vital; Konstantinos Markou Journal: Case Rep Otolaryngol Date: 2013-04-04
Authors: Afonso Nóbrega Dantas; Everton Freitas de Morais; Rômulo Augusto de Paiva Macedo; João Maria de Lima Tinôco; Maria de Lourdes Silva de Arruda Morais Journal: Braz J Otorhinolaryngol Date: 2015-03-30