Literature DB >> 10762048

Eryloside F, a novel penasterol disaccharide possessing potent thrombin receptor antagonist activity.

P Stead1, S Hiscox, P S Robinson, N B Pike, P J Sidebottom, A D Roberts, N L Taylor, A E Wright, S A Pomponi, D Langley.   

Abstract

We report the discovery of Eryloside F, a novel disaccharide of the steroidal carboxylic acid penasterol, isolated from an extract of the marine sponge Erylus formosus. The compound is a potent thrombin receptor antagonist, and furthermore inhibits human platelet aggregation in vitro.

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Year:  2000        PMID: 10762048     DOI: 10.1016/s0960-894x(00)00063-9

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  12 in total

Review 1.  Marine pharmacology in 2000: marine compounds with antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiplatelet, antituberculosis, and antiviral activities; affecting the cardiovascular, immune, and nervous systems and other miscellaneous mechanisms of action.

Authors:  Alejandro M S Mayer; Mark T Hamann
Journal:  Mar Biotechnol (NY)       Date:  2003-11-03       Impact factor: 3.619

Review 2.  Bioactive sesterterpenes and triterpenes from marine sponges: occurrence and pharmacological significance.

Authors:  Sherif S Ebada; Wenhan Lin; Peter Proksch
Journal:  Mar Drugs       Date:  2010-02-23       Impact factor: 5.118

Review 3.  Glycosides from marine sponges (Porifera, Demospongiae): structures, taxonomical distribution, biological activities and biological roles.

Authors:  Vladimir I Kalinin; Natalia V Ivanchina; Vladimir B Krasokhin; Tatyana N Makarieva; Valentin A Stonik
Journal:  Mar Drugs       Date:  2012-08-10       Impact factor: 6.085

Review 4.  Natural Products for Antithrombosis.

Authors:  Cen Chen; Feng-Qing Yang; Qian Zhang; Feng-Qin Wang; Yuan-Jia Hu; Zhi-Ning Xia
Journal:  Evid Based Complement Alternat Med       Date:  2015-05-17       Impact factor: 2.629

5.  The antimicrobial activity of heterotrophic bacteria isolated from the marine sponge Erylus deficiens (Astrophorida, Geodiidae).

Authors:  Ana Patrícia Graça; Flávia Viana; Joana Bondoso; Maria Inês Correia; Luis Gomes; Madalena Humanes; Alberto Reis; Joana R Xavier; Helena Gaspar; Olga M Lage
Journal:  Front Microbiol       Date:  2015-05-07       Impact factor: 5.640

Review 6.  Marine invertebrate natural products for anti-inflammatory and chronic diseases.

Authors:  Kalimuthu Senthilkumar; Se-Kwon Kim
Journal:  Evid Based Complement Alternat Med       Date:  2013-12-31       Impact factor: 2.629

Review 7.  Marine Sponges as a Drug Treasure.

Authors:  Komal Anjum; Syed Qamar Abbas; Sayed Asmat Ali Shah; Najeeb Akhter; Sundas Batool; Syed Shams Ul Hassan
Journal:  Biomol Ther (Seoul)       Date:  2016-07-01       Impact factor: 4.634

Review 8.  Marine sponges as pharmacy.

Authors:  Detmer Sipkema; Maurice C R Franssen; Ronald Osinga; Johannes Tramper; René H Wijffels
Journal:  Mar Biotechnol (NY)       Date:  2005-03-24       Impact factor: 3.619

9.  Antimicrobial activity of heterotrophic bacterial communities from the marine sponge Erylus discophorus (Astrophorida, Geodiidae).

Authors:  Ana Patrícia Graça; Joana Bondoso; Helena Gaspar; Joana R Xavier; Maria Cândida Monteiro; Mercedes de la Cruz; Daniel Oves-Costales; Francisca Vicente; Olga Maria Lage
Journal:  PLoS One       Date:  2013-11-13       Impact factor: 3.240

10.  Poecillastrosides, Steroidal Saponins from the Mediterranean Deep-Sea Sponge Poecillastra compressa (Bowerbank, 1866).

Authors:  Kevin Calabro; Elaheh Lotfi Kalahroodi; Daniel Rodrigues; Caridad Díaz; Mercedes de la Cruz; Bastien Cautain; Rémi Laville; Fernando Reyes; Thierry Pérez; Bassam Soussi; Olivier P Thomas
Journal:  Mar Drugs       Date:  2017-06-26       Impact factor: 5.118

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