Literature DB >> 10761496

Physostigmine in the treatment of gamma-hydroxybutyric acid overdose.

S W Yates1, A J Viera.   

Abstract

The widespread abuse of the recreational drug gamma-hydroxybutyric acid has resulted in several reports of overdose leading to coma. The use of a short-acting anticholinesterase agent such as physostigmine as a potential reversal agent has been proposed previously. We report 2 cases of gamma-hydroxybutyric acid-induced coma that rapidly reversed with intravenous administration of physostigmine.

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Year:  2000        PMID: 10761496     DOI: 10.4065/75.4.401

Source DB:  PubMed          Journal:  Mayo Clin Proc        ISSN: 0025-6196            Impact factor:   7.616


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