J C Dixon1, D M Penman, P W Soothill. 1. Department of Obstetrics and Gynaecology, University of Bristol, St. Michael's Hospital, UK.
Abstract
OBJECTIVES: To investigate the relationship between intestinal atresia and fetal growth, intrapartum cardiotocograph abnormalities and staining of the amniotic fluid in gastroschisis pregnancies. DESIGN: Observational study of 115 gastroschisis pregnancies conceived between 1980 and 1996. SETTING: South West Region of England. MAIN OUTCOME MEASURES: Birthweight, intrapartum cardiotocograph abnormality, staining of amniotic fluid and Apgar score. RESULTS: There was no statistically significant difference between the Apgar scores or the frequency of amniotic fluid staining of gastroschisis cases with or without atresia. Patent bowel gastroschisis was associated significantly with more cardiotocograph abnormalities (61% vs 26%, P = 0.026) and reduced growth (P = 0.02), when compared with cases with intestinal atresia. CONCLUSIONS: Bile vomiting may be an important cause of amniotic fluid staining. Bowel atresia protects against the increased incidence of cardiotocograph and growth abnormality found in cases of gastroschisis which may reflect their aetiology.
OBJECTIVES: To investigate the relationship between intestinal atresia and fetal growth, intrapartum cardiotocograph abnormalities and staining of the amniotic fluid in gastroschisis pregnancies. DESIGN: Observational study of 115 gastroschisis pregnancies conceived between 1980 and 1996. SETTING: South West Region of England. MAIN OUTCOME MEASURES: Birthweight, intrapartum cardiotocograph abnormality, staining of amniotic fluid and Apgar score. RESULTS: There was no statistically significant difference between the Apgar scores or the frequency of amniotic fluid staining of gastroschisis cases with or without atresia. Patent bowel gastroschisis was associated significantly with more cardiotocograph abnormalities (61% vs 26%, P = 0.026) and reduced growth (P = 0.02), when compared with cases with intestinal atresia. CONCLUSIONS:Bile vomiting may be an important cause of amniotic fluid staining. Bowel atresia protects against the increased incidence of cardiotocograph and growth abnormality found in cases of gastroschisis which may reflect their aetiology.