| Literature DB >> 10758942 |
R B Rothman1, J B Redmon, S K Raatz, C A Kwong, J E Swanson, J P Bantle.
Abstract
As expected on the basis of published research in both humans and animals, treatment with phentermine/fenfluramine lowers plasma 5-hydroxytryptamine [corrected], whereas treatment with phentermine had no significant effect. In light of these findings, future research should focus on mechanisms other than increased plasma 5-hydroxytryptamine [corrected] to explain how fenfluramine increases the risk of primary pulmonary hypertension and valvular heart disease.Entities:
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Year: 2000 PMID： 10758942 DOI： 10.1016/s0002-9149(99)00896-6
Source DB: PubMed Journal: Am J Cardiol ISSN： 0002-9149 Impact factor: 2.778