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Literature DB >> 10758408

The macrophage receptor MARCO.

G Kraal¹, L J van der Laan, O Elomaa, K Tryggvason.

Abstract

MARCO (macrophage receptor with collagenous structure) belongs to the class A scavenger receptor molecules. The structure and function of the molecule is described. Although it is expressed on subsets of macrophages, it can be upregulated on other macrophages after bacterial infection. The strategic position of MARCO-expressing cells in lymphoid organs suggests an important role for this bacteria-binding molecule in removal of pathogens.

Entities: Disease Gene

Mesh：

Substances：

Year: 2000 PMID： 10758408 DOI： 10.1016/s1286-4579(00)00296-3

Source DB: PubMed Journal: Microbes Infect ISSN： 1286-4579 Impact factor: 2.700

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Cited

48 in total

1. Transcriptional changes that characterize the immune reactions of leprosy.

Authors: Kathryn M Dupnik; Thomas B Bair; Andressa O Maia; Francianne M Amorim; Marcos R Costa; Tatjana S L Keesen; Joanna G Valverde; Maria do Carmo A P Queiroz; Lúcio L Medeiros; Nelly L de Lucena; Mary E Wilson; Mauricio L Nobre; Warren D Johnson; Selma M B Jeronimo
Journal: J Infect Dis Date: 2014-11-14 Impact factor: 5.226

2. The -112G>A polymorphism of the secretoglobin 3A2 (SCGB3A2) gene encoding uteroglobin-related protein 1 (UGRP1) increases risk for the development of Graves' disease in subsets of patients with elevated levels of immunoglobulin E.

Authors: Dimitry A Chistiakov; Natalia V Voronova; Rust I Turakulov; Kirill V Savost'anov
Journal: J Appl Genet Date: 2010-12-18 Impact factor: 3.240

3. Effective collaboration between marginal metallophilic macrophages and CD8+ dendritic cells in the generation of cytotoxic T cells.

Authors: Ronald Backer; Timo Schwandt; Mascha Greuter; Marije Oosting; Frank Jüngerkes; Thomas Tüting; Louis Boon; Tom O'Toole; Georg Kraal; Andreas Limmer; Joke M M den Haan
Journal: Proc Natl Acad Sci U S A Date: 2009-12-14 Impact factor: 11.205

Review 4. Role of microglia in neuronal degeneration and regeneration.

Authors: Lisa Walter; Harald Neumann
Journal: Semin Immunopathol Date: 2009-09-09 Impact factor: 9.623

5. Class A scavenger receptor expression and function in eight novel tadpole cell lines from the green frog (Lithobates clamitans) and the wood frog (Lithobates sylvatica).

Authors: Nguyen T K Vo; Joshua Everson; Levi Moore; Stephanie J DeWitte-Orr
Journal: Cytotechnology Date: 2019-06-06 Impact factor: 2.058

The macrophage receptor MARCO.

1. Transcriptional changes that characterize the immune reactions of leprosy.

2. The -112G>A polymorphism of the secretoglobin 3A2 (SCGB3A2) gene encoding uteroglobin-related protein 1 (UGRP1) increases risk for the development of Graves' disease in subsets of patients with elevated levels of immunoglobulin E.

3. Effective collaboration between marginal metallophilic macrophages and CD8+ dendritic cells in the generation of cytotoxic T cells.

Review 4. Role of microglia in neuronal degeneration and regeneration.

5. Class A scavenger receptor expression and function in eight novel tadpole cell lines from the green frog (Lithobates clamitans) and the wood frog (Lithobates sylvatica).

6. Genomics of immune response to typhoid and cholera vaccines.

Review 7. Sinusoidal immunity: macrophages at the lymphohematopoietic interface.

8. Acute appendicitis is characterized by a uniform and highly selective pattern of inflammatory gene expression.

9. Genomic correlates of variability in immune response to an oral cholera vaccine.

10. Targeting MARCO can lead to enhanced dendritic cell motility and anti-melanoma activity.