OBJECTIVES: Mitral-valve repair in Barlow's disease is challenging; conventional techniques are difficult to perform, and there is a high risk of a postoperative suboptimal result. Double-orifice repair has been applied in a standardized approach to treat patients with severe mitral regurgitation and bileaflet prolapse due to Barlow's disease. METHODS: Since 1993, 82 patients with severe mitral regurgitation due to Barlow's disease underwent correction applying the edge-to-edge concept. They were submitted to double-orifice repair in a standardized fashion, suturing the middle portions of both leaflets. RESULTS: There were no hospital deaths. The repair was unsatisfactory in one patient who underwent valve replacement soon after the repair. The mean postoperative valve area was 3.7+/-0.79 cm(2) against a mean preoperative value of 9.2+/-2.1 cm(2). No or mild regurgitation was found in all but three patients who showed moderate residual regurgitation. There were no late deaths. Freedom from reoperation was 86+/-14% at 5 years. At the latest follow-up, all patient but one were New York Heart Association (NYHA) functional class I, and echo-Doppler assessment of valve reconstruction showed stable valve function in all patients. CONCLUSIONS: The double-orifice repair can be used as a standardized approach to treat valve regurgitation due to Barlow disease with low risk and good early and mid-term results.
OBJECTIVES: Mitral-valve repair in Barlow's disease is challenging; conventional techniques are difficult to perform, and there is a high risk of a postoperative suboptimal result. Double-orifice repair has been applied in a standardized approach to treat patients with severe mitral regurgitation and bileaflet prolapse due to Barlow's disease. METHODS: Since 1993, 82 patients with severe mitral regurgitation due to Barlow's disease underwent correction applying the edge-to-edge concept. They were submitted to double-orifice repair in a standardized fashion, suturing the middle portions of both leaflets. RESULTS: There were no hospital deaths. The repair was unsatisfactory in one patient who underwent valve replacement soon after the repair. The mean postoperative valve area was 3.7+/-0.79 cm(2) against a mean preoperative value of 9.2+/-2.1 cm(2). No or mild regurgitation was found in all but three patients who showed moderate residual regurgitation. There were no late deaths. Freedom from reoperation was 86+/-14% at 5 years. At the latest follow-up, all patient but one were New York Heart Association (NYHA) functional class I, and echo-Doppler assessment of valve reconstruction showed stable valve function in all patients. CONCLUSIONS: The double-orifice repair can be used as a standardized approach to treat valve regurgitation due to Barlow disease with low risk and good early and mid-term results.
Authors: H Kamiya; Payam Akhyari; J-P Minol; A C Ites; T Weinreich; S Sixt; P Rellecke; U Boeken; A Albert; A Lichtenberg Journal: Gen Thorac Cardiovasc Surg Date: 2017-03-22
Authors: Corrado Tamburino; Gian Paolo Ussia; Francesco Maisano; Davide Capodanno; Giovanni La Canna; Salvatore Scandura; Antonio Colombo; Andrea Giacomini; Iassen Michev; Sarah Mangiafico; Valeria Cammalleri; Marco Barbanti; Ottavio Alfieri Journal: Eur Heart J Date: 2010-03-18 Impact factor: 29.983
Authors: Serguei I Melnitchouk; Joerg Seeburger; Anna F Kaeding; Martin Misfeld; Friedrich W Mohr; Michael A Borger Journal: Ann Cardiothorac Surg Date: 2013-11